ArticleBMC oral health2025
Association of tooth brushing behavior with risks of major chronic health outcomes: a scoping review.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oral Health in Early and Advanced Stages (1-4) of Chronic Kidney Disease: A Systematic Review and Meta-Analysis.International dental journal · 2026Pooled it
- Chewing function, diet quality, and risk of metabolic syndrome and mortality: analysis of NHANES 1999-2018.BMC oral health · 2026Article
- Association between tooth brushing habits and incident disability in community-dwelling older adults: a prospective cohort study.Environmental health and preventive medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOral hygiene behavior has been increasingly recognized as a potential contributor to chronic disease prevention. This scoping review aimed to synthesize existing evidence on the associations between tooth brushing behavior (as a proxy for oral hygiene) and major chronic health outcomes, including cardiovascular events (e.g., myocardial infarction, atrial fibrillation, heart failure), stroke (ischemic, hemorrhagic, and subarachnoid), hypertension (HTN), metabolic syndrome (MetS), and chronic kidney disease (CKD).
methodsA comprehensive literature search was conducted using four databases: Ovid-MEDLINE, EMBASE, CINAHL, and the Cochrane Library. The study selection process followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Two reviewers independently screened and selected eligible studies and extracted relevant data. A total of 142 full-text articles were assessed for eligibility.
resultsTwenty-one studies were included in the final review. Most studies reported that a lower frequency of tooth brushing was associated with a higher risk of cardiovascular events, stroke, HTN, MetS, and CKD. Additionally, several studies suggested that maintaining good oral hygiene in individuals with HTN or diabetes mellitus (DM) may be associated with a reduced risk of cardiovascular complications.
conclusionFrequent tooth brushing, as a key component of oral hygiene, may be associated with a reduced risk of several chronic health outcomes, particularly cardiovascular and metabolic diseases. However, the current body of evidence is predominantly based on observational studies. Further longitudinal and interventional research is warranted to clarify the directionality and potential causal pathways linking oral hygiene behavior to systemic health outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.