ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2025
Supramolecular Assembly of Dendrobium officinale Polysaccharides-Hyaluronic Acid and Its Moisturizing Properties.
Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Merits of bioactivity and products ofFrontiers in plant science · 2026Pooled it
- Dendrobium and Orchidaceae Plants in Dermatology: A PubMed-Based Bibliometric Analysis and Mechanistic Overview.Clinical, cosmetic and investigational dermatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSupramolecular technology has been widely applied in cosmetics due to its ability to enhance the stability of active substances and reduce their irritation potential. The synergistic interaction between polysaccharides can produce new products with characteristics and rheological properties that make them suitable for various applications.
objectiveThe supramolecularly assembly of Dendrobium officinale polysaccharide (DOP) and hyaluronic acid (HA) was produced, and its moisturizing effect was verified to provide a basis for the application of supramolecular technology in cosmetic functional raw materials.
methodsThe supramolecular structure of polysaccharide assembly samples was verified through scanning electron microscopic observation. Moisture absorption and the ability of samples to resist cell drying damage before and after supramolecular assembly were evaluated by moisture absorption experiments and a cell drying damage model, respectively. Furthermore, this study validated the moisturizing effect of the supramolecular compositions during their application in cosmetics through tests of skin moisture content in extremely dry environments (during the winter season of Beijing, China), skin roughness and scale index, and trans epidermal water loss.
resultsThe supramolecular composition appeared as a large sheet-like structure under a scanning electron microscope. Further, the supramolecular composition had significantly improved moisture absorption performance and could effectively resist cell drying damage. In an extremely dry environment, the composition showed excellent moisturizing performance and effectively improved skin scale and roughness.
conclusionsThe supramolecular assembly of DOP and HA has a synergistic moisturizing effect; thus, it can be expected to have a good moisturizing effect when applied to cosmetics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.