Evidence map›Paper›PMID 40484429›Full record

ArticleBMJ open2025

Economic burden of hypertension in Iran: a prevalence-based cost of illness study.

Rajabali Daroudi, Ali AkbariSari, Mahmoud Zamandi, Zahra Shahali

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rajabali DaroudiDepartment of Health Management, Policy and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of).ORCID http://orcid.org/0000-0002-0487-4114
Ali AkbariSariDepartment of Health Management, Policy and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of).ORCID http://orcid.org/0000-0001-7755-7665
Mahmoud ZamandiDepartment of Health Management, Policy and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of) mzamandi8@gmail.com.ORCID http://orcid.org/0000-0003-1675-3026
Zahra ShahaliDepartment of Health Insurance, National Center for Health Insurance Research, Tehran, Iran (the Islamic Republic of).ORCID http://orcid.org/0000-0002-5457-5999

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHypertension is one of the silent diseases and is the major cause of many chronic conditions. The treatment services for hypertension and its cardiovascular complications impose high costs on society and the health system. However, in LMCs, there is not enough evidence-based information about the costs of high blood pressure. This study aims to assess the economic burden of hypertension in Iran in 2020.

designA prevalence-based cost of illness study.

settingData on hypertension and selected diseases, including their prevalence, incidence, mortality risk and death counts, were sourced from literature reviews, the Global Burden of Disease (GDP) and the Non-Communicable Diseases Research Centre. Cost estimates were derived from health insurance data, surveys, research studies and treatment protocols. Additional data, such as population, employment rates, household activity rates, wage rates and GDP per capita, were obtained from the Statistical Centre of Iran and the World Bank. PARTICIPANTS AND

methodsA prevalence-based cost of illness study was used to estimate the economic burden of hypertension. The focus was on the most significant diseases associated with high blood pressure, including coronary heart disease, ischaemic stroke, haemorrhagic stroke and the direct costs of hypertension. Subsequently, the total number of patients was multiplied by the average cost per patient for each disease. To calculate the average cost, inpatient and outpatient, direct non-medical and indirect costs of diseases were estimated and multiplied by a population-attributed fraction of high blood pressure. Direct costs (hospitalisation and outpatient costs and direct non-medical costs) of hypertension were calculated using the bottom-up approach, and the human capital approach was used to calculate indirect costs.

resultsAccording to the results of the study, the total economic burden of hypertension was $ purchasing power parity (PPP) 12 848.22 million, of which the share of direct medical, non-medical and indirect costs of hypertension were $ PPP 7245.13 million (56.4%), $ PPP 1173.42 million (9.1%) and $ PPP 4429.68 million (34.5%), respectively. The total economic burden of high blood pressure was equal to 23% of the total economic burden of four chronic diseases.

conclusionThe economic burden of high blood pressure in the country is very high and significant, and it was equivalent to about 1% of the country's gross domestic product in 2020, which shows the necessity of preventive interventions.

Indexed as

Cost of IllnessHealth Care CostsHypertensionAdultFemaleHumansIranMaleMiddle AgedPrevalenceHealth Care CostsHEALTH ECONOMICSHealth policy

Identifiers

PMID40484429
PMCPMC12161342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.