Differences in the autonomic regulation of temperature in the lower lip and tongue during activation of the lingual nerve.

Syed Taufiqul Islam, Toshiya Sato, Hanako Ohke, Mari Shimatani, Hisayoshi Ishii

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Article in The journal of physiological sciences : JPS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Syed Taufiqul IslamDivision of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan.

Toshiya SatoDivision of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan.

Hanako OhkeDivision of Dental Anesthesiology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan.

Mari ShimataniDivision of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan.

Hisayoshi IshiiDivision of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan. Electronic address: hisayosh@hoku-iryo-u.ac.jp.

Funding

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6 · The paper itself

Abstract

Orofacial temperature influences orofacial functions and is related to hemodynamics mediated by the autonomic nerves. Although the properties of autonomic vasomotor responses differ in orofacial tissues, differences in the autonomic regulation of orofacial temperature are unclear. We examined the differences in blood flow (BF) and temperature (Tm) between the extraoral (lower lip) and intraoral tissues (tongue) of urethane-anesthetized rats. Noncholinergic parasympathetic vasodilation evoked by trigeminal-mediated reflex elicited significant increases in BF and Tm in both tissues, and these increases were larger in the tongue than in the lower lip. Activation of cervical sympathetic nerves significantly decreased BF and Tm in both tissues. These decreases were restored by parasympathetic reflex vasodilation; the effects were larger in the tongue than in the lower lip. Our results suggest that parasympathetic vasodilation is involved in the maintenance of BF and Tm, and that the effects may be greater in intraoral than in extraoral tissues.

Indexed as

Autonomic Nervous SystemBody TemperatureBody Temperature RegulationLingual NerveLipTongueAnimalsMaleRatsRats, Sprague-DawleyRegional Blood FlowVasodilationCervical sympathetic nervesNoncholinergic parasympathetic vasodilationOrofacial temperatureTrigeminal mediated reflex

Identifiers

PMID40483984

DOI10.1016/j.jphyss.2025.100028

PMCPMC12177167

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