Evidence map›Paper›PMID 40483493›Full record

ArticleWorld journal of emergency surgery : WJES2025

Effects of the lavage through fistula in treatment of spontaneous esophageal rupture by combined thoracoscopic and gastroscopic management.

Zhao Huang, Penglong Zhao, Bingmei Qiu, Chuan Gao, Zhao Chen, Nan Yang, Yang Xu, Zhiqiang Zou, Yi Shen, Liwen Hu

Abstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhao Huang *Department of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Penglong Zhao *Department of Cardiothoracic Surgery, Jinling Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China.
Bingmei Qiu *Department of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Chuan GaoDepartment of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Zhao ChenDepartment of Cardiothoracic Surgery, The 960th Hospital of PLA, Jinan, Shandong Province, China.
Nan YangDepartment of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Yang XuDepartment of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Zhiqiang Zou *Department of Cardiothoracic Surgery, The 960th Hospital of PLA, Jinan, Shandong Province, China. Zzqxwk@163.com.
Yi Shen *Department of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China. dryishen@nju.edu.cn.
Liwen HuDepartment of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China. thorax_hoo@163.com.

Funding

the Clinical research project from Jinling Hospital, Medical School of Nanjing University 22LCYY-XH6the key project of basic research from Jinling Hospital, Medical School of Nanjing University 22JCYYZD5the key project of Jiangsu Commission of Health BK20181239
6 · The paper itself

Abstract

backgroundSpontaneous esophageal rupture (SER) is a rare and severe emergency with high mortality, and the treatment algorithm remains controversial.

methodsThis retrospective study analyzed SER cases that underwent VATS debridement and drainage in Jinling Hospital from January 2014 to July 2024. Patients were divided into Lavage-Drainage and Drainage groups based on whether they received a lavage tube cathetering through the esophageal fistula under gastroscope. Preoperative fluid resuscitation, thoracoscopic mediastinotomy, and thoracic debridement were performed. Post-operative management included fasting, enteral nutrition, anti-infective agents, and fluid and electrolyte balance maintenance. Monitoring indicators included vital signs, laboratory test results, postoperative complications, and other relevant factors.

resultsA total of 24 patients were enrolled, with 11 in the Lavage-Drainage group and 13 in the Drainage group. The Lavage-Drainage group had lower 30-day mortality, fewer complications and adverse events, and a faster reduction in inflammatory factors, but a higher cost. There was no significant difference in the length of mechanical ventilation, hospital stay, and ICU stay.

conclusionsThe Lavage-Drainage approach enhanced the drainage efficiency, reduced the inflammation level, and improved the prognosis of SER. However, this study has some limitations, and further multi-center prospective studies are needed to optimize the treatment and reduce costs.

Indexed as

GastroscopyTherapeutic IrrigationAdultAgedDrainageFemaleHumansMaleMiddle AgedRetrospective StudiesRupture, SpontaneousTreatment OutcomeBoerhaave’s syndromeGastroscopySpontaneous rupture of the esophagusThoracoscopyVideo-assisted thoracoscopic surgery (VATS)

Identifiers

PMID40483493
PMCPMC12145610

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.