Evidence map›Paper›PMID 40483405›Full record

SynthesisBMC women's health2025

The impact of diabetes on postoperative outcomes following hysterectomy: a systematic review and meta-analysis.

Yuhuan Zeng, Yuanhu Lei, Min Li, Wei Liu, Jie Zhou, Jie Zhong, Guangming Song, Yukun Li, Xiangfang Tan, Qunfeng Zhang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuhuan Zeng *The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Yuanhu Lei *The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Min Li *The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Wei LiuThe Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Jie ZhouThe Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Jie ZhongThe Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Guangming SongThe Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Yukun LiThe Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China.
Xiangfang TanThe Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China. tanxiangfang02@163.com.
Qunfeng ZhangThe Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang City, Hunan Province, China. xiaofeng29@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlthough diabetes mellitus (DM) is considered an important prognostic factor for hysterectomy outcomes, the relationship between DM and postoperative complications remains unclear. The aim of this study was to investigate whether DM is associated with an increased risk of complications following hysterectomy.

methodsWe systematically searched PubMed, Embase, and the Cochrane Library for relevant articles published on or before March 15, 2024. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated via random effects meta-analysis. The primary outcome was the risk of complications posthysterectomy, including postoperative infection and hospital readmission. Additionally, we conducted subgroup and sensitivity analyses to explore the main sources of heterogeneity and assess the stability of the results.

resultsA total of 19 cohort studies comprising 375,531 participants met the inclusion criteria. This meta-analysis revealed that DM was significantly associated with postoperative infection (OR 2.01, 95% CI 1.46-2.77). Additionally, DM was significantly associated with low postoperative survival (5 years) (OR 4.43, 95% CI 2.98-6.58), readmission (OR 1.59, 95% CI 1.42-1.79), embolism (OR 1.31, 95% CI 1.18-1.46), renal failure (OR 3.88, 95% CI 2.74-5.51) and reintubation (OR 3.23, 95% CI 1.64-6.35), whereas DM was not associated with an extended length of stay (OR 1.39, 95% CI 0.93-2.10), myocardial infarction (OR 1.86, 95% CI 0.58-5.98) or blood transfusion (OR 1.36, 95% CI 0.88-2.11) in patients following hysterectomy.

conclusionsDM increases the risk of postoperative infection following hysterectomy. Special attention should be given to diabetic patients to reduce the incidence of complications after hysterectomy.

Indexed as

Diabetes MellitusHysterectomyPostoperative ComplicationsFemaleHumansPatient ReadmissionRisk FactorsDiabetes mellitus, Hysterectomy, Postoperative complication, infection, Meta-analysis

Identifiers

PMID40483405
PMCPMC12145621

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.