Evidence map›Paper›PMID 40483339›Full record

ArticleFolia microbiologica2026

Repurposing of quinine as an antifungal antibiotic: Identification of molecular targets in Candida albicans.

Sargun Basrani, Shivani Patil, Sayali Chougule, Tanjila Kotalagi, Shivanand Yankanchi, Sankunny Mohan Karuppayil, Ashwini K Jadhav

Abstract read
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In one paragraph

Article in Folia microbiologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sargun BasraniDepartment of Stem Cell and Regenerative Medicine, and Medical Biotechnology, Centre for Interdisciplinary Research, D.Y. Patil Education Society (Deemed to Be University), Kolhapur, Maharashtra, India, 416006.
Shivani PatilDepartment of Stem Cell and Regenerative Medicine, and Medical Biotechnology, Centre for Interdisciplinary Research, D.Y. Patil Education Society (Deemed to Be University), Kolhapur, Maharashtra, India, 416006.
Sayali ChouguleDepartment of Stem Cell and Regenerative Medicine, and Medical Biotechnology, Centre for Interdisciplinary Research, D.Y. Patil Education Society (Deemed to Be University), Kolhapur, Maharashtra, India, 416006.
Tanjila KotalagiDepartment of Stem Cell and Regenerative Medicine, and Medical Biotechnology, Centre for Interdisciplinary Research, D.Y. Patil Education Society (Deemed to Be University), Kolhapur, Maharashtra, India, 416006.
Shivanand YankanchiDepartment of Zoology, Shivaji University, Vidyanagar, Kolhapur, Maharashtra, 416004, India.
Sankunny Mohan KaruppayilDepartment of Stem Cell and Regenerative Medicine, and Medical Biotechnology, Centre for Interdisciplinary Research, D.Y. Patil Education Society (Deemed to Be University), Kolhapur, Maharashtra, India, 416006.
Ashwini K JadhavDepartment of Stem Cell and Regenerative Medicine, and Medical Biotechnology, Centre for Interdisciplinary Research, D.Y. Patil Education Society (Deemed to Be University), Kolhapur, Maharashtra, India, 416006. ashujadhav09@gmail.com.ORCID http://orcid.org/0000-0003-4204-301X

Funding

D.Y. Patil Education Society Institution Deemed to be University Kolhapur DYPES/DU/R&D/1154
6 · The paper itself

Abstract

Quinine, a component of the bark of the cinchona tree, is commonly used to treat malaria. The present study focused on the identification of anti-Candida albicans activity of quinine and its mechanism of action. Quinine showed planktonic growth inhibitory activity at 0.5 mg/mL and fungicidal activity at 4 mg/mL concentration. Time-dependent killing of C. albicans cells was seen after the treatment of quinine at 4 mg/mL concentration. The MIC

Indexed as

Antifungal AgentsCandida albicansDrug RepositioningQuinineAnimalsBiofilmsCandidiasisHyphaeMicrobial Sensitivity TestsAntifungal AgentsQuinineAntifungal agentCandida albicansCell cycleMultitargetingQuinineRepurposing

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.