ArticleScientific data2025
High resolution multi-parametric probabilistic in vivo atlas of dorsolateral nigral hyperintensity via 7 T MRI.
Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- The swallow tail sign: mechanisms, neuroimaging advances and future perspectives.Insights into imaging · 2026Article
- Sex-dependent dopaminergic vulnerability may contribute to sex differences in Parkinson's disease risk.Brain communications · 2026Article
- High resolution multi-parametric probabilistic in vivo atlas of dorsolateral nigral hyperintensity via 7 T MRI.Scientific data · 2025Article
- Ferroptosis in central nervous system injuries: molecular mechanisms, diagnostic approaches, and therapeutic strategies.Frontiers in cellular neuroscience · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
The role of Nigrosome 1 (N1) in neurodegeneration and motor disorders, particularly in Parkinson's disease (PD), is increasingly recognized. The study of this region using quantitative measures, such as iron quantification through Quantitative Susceptibility Mapping (QSM), can provide enlightening insights into some pathological features of these diseases representing important biomarkers. However, the small size and the vanishing contrast with respect to the surrounding substantia nigra in PD patients make the segmentation of N1 challenging. For this reason, we provide a probabilistic atlas of the N1 portion corresponding to the swallow-tail hyperintensity, hereafter referred to as the Dorsolateral Nigral Hyperintensity (DNH), created on a high-resolution multi-parametric template from T1-weighted, T2*-weighted, and QSM images acquired in vivo at 7 T. The atlas also includes quantitative T2* and R2* templates and is provided in the MNI standard space. It aims to facilitate the study of N1, avoiding operator-dependent biases in segmentations, and allowing the standardisation of the quantitative assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.