ReviewJournal of advanced research2026
A comprehensive examination of the impact of environmental pollution on lung cancer: A review.
Review in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Marine microplastic pollution and cancer incidence from 2013 to 2021 in US coastal counties: an ecological analysis.International journal of hygiene and environmental health · 2026Article
- Diverging Trajectories of Lung Cancer Burden in China, Japan, and South Korea: A Comparative Risk Assessment from the Global Burden of Disease Study 1990-2021.Thoracic cancer · 2026Article
- Review
- Review
- Identifying early-life, environmental, and social stressors as key predictors of U.S. respiratory failure mortality: a machine learning study.Frontiers in public health · 2026Article
- Association of physical component score with high-risk lung nodules among Chinese Urban sanitation workers: a sex-specific analysis.Frontiers in public health · 2026Article
- Targeting chemical carcinogenesis: α-pinene and D-limonene as chemopreventive agents against NNK/TCDD- and urethane-induced lung tumorigenesis.Journal of food and drug analysis · 2025Article
- Review
- Effect of Particulate Matter Pollution on Global Lung Cancer Burden: A Systematic Analysis for the Global Burden of Disease Study 1990-2021.Thoracic cancer · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLung cancer is a leading cause of death worldwide, with environmental factors playing critical roles in its development and progression. Respirable and food-borne contaminants are major contributors to lung cancer onset, influencing various physiological pathways that lead to lung injury and tumor formation. AIM OF REVIEW: This review aims to examine the effects of common environmental pollutants on lung cancer development, highlighting the role of specific contaminants, such as PM2.5 (particulate matter with aerodynamic diameter less than 2.5 µm) and nitrogen oxides, and warning people to pay more attention to environmental pollutants. KEY SCIENTIFIC CONCEPTS OF REVIEW: Environmental pollutants play a significant role in increasing the susceptibility to lung cancer by triggering various biological mechanisms that lead to lung injury and tumorigenesis. Excessive PM2.5 exposure contributes to the overall burden of lung cancer via Wnt/β-catenin, Reactive oxygen species-DNA methyltransferases (ROS-DNMT), phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt), Janus kinase/signal transducers and activators of transcription (JAK/STAT) signalling pathways. The primary mechanisms by which NO contributes to the occurrence and development of pulmonary neoplasm revolve around the production and regulation of ROS. Occupational exposure and ecosystem pollution to hazardous substances, including microplastics, pesticides, asbestos, cadmium, and nickel, are the well-established risk factors for the development of lung cancer via DNA damage, oxidative stress, and inflammation pathways. This review emphasizes the importance of effective prevention strategies for lung cancer by reducing environmental pollution levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.