Evidence map›Paper›PMID 40482431›Full record

ArticleDrug metabolism and disposition: the biological fate of chemicals2025

Predicting in vivo cannabinoid-drug interactions mediated via inhibition of UDP-glucuronosyltransferases using in vitro studies and physiologically based pharmacokinetic modeling and simulations.

Sumit Bansal, Mary F Paine, Jashvant D Unadkat

Abstract read
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In one paragraph

Article in Drug metabolism and disposition: the biological fate of chemicals, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sumit BansalDepartment of Pharmaceutics, University of Washington, Seattle, Washington.
Mary F PaineDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington; Center of Excellence for Natural Product Drug Interaction Research, Washington State University, Spokane, Washington.
Jashvant D UnadkatDepartment of Pharmaceutics, University of Washington, Seattle, Washington; Center of Excellence for Natural Product Drug Interaction Research, Washington State University, Spokane, Washington. Electronic address: jash@uw.edu.

Funding

Pharmacology CoreU54AT008909 · NCCIH · WASHINGTON STATE UNIVERSITY · PI PAINE, MARY F · 2015 to 2024
$22.4M
Understanding Fetal Exposure to Cannabinoids Through In Vitro and In Vivo StudiesP01DA032507 · NIDA · UNIVERSITY OF WASHINGTON · PI UNADKAT, JASHVANT D · 2013 to 2023
$12.4M
NCCIH NIH HHS U54 AT008909NIDA NIH HHS P01 DA032507
6 · The paper itself

Abstract

We previously reported the inhibitory potential of the most extensively studied cannabinoids, cannabidiol (CBD) and Δ

Indexed as

CannabidiolCannabinoidsDronabinolGlucuronosyltransferaseModels, BiologicalAnimalsComputer SimulationDrug InteractionsHumansMaleMicrosomes, LiverCannabidiolCannabinoidsDronabinolGlucuronosyltransferasecannabidiolCannabinoidsDrug−drug interactionsIn vitro to in vivo prediction of cannabinoid-drug interactionsPhysiologically based pharmacokinetic modelingUridine 5′-diphosphoglucuronosyltransferasesΔ(9)-tetrahydrocannabinol

Identifiers

PMID40482431
PMCPMC13632506

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.