Evidence map›Paper›PMID 40481849›Full record

SynthesisNeurosurgical review2025

Glue-transposition technique for hemifacial spasm involving vertebrobasilar dolichoectasia: a comparative study and literature review.

Wen-Jian Zheng, Rui He, Xiejun Zhang, Fanfan Chen, Lei Chen, Yufei Liu, Jihu Yang, Zhong Deng, Taipeng Jiang, Guodong Huang

Abstract readComparative StudySystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wen-Jian Zheng *Department of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Rui He *Department of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Xiejun ZhangDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Fanfan ChenDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Lei ChenDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Yufei LiuDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Jihu YangDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Zhong DengDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Taipeng JiangDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China.
Guodong HuangDepartment of Neurosurgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, Guangdong, 518035, P.R. China. huangguodong@email.szu.edu.cn.

Funding

Sanming Project of Medicine in Shenzhen No. SZSM202011018Shenzhen Key Medical Discipline Construction Fund No. SZGSP002
6 · The paper itself

Abstract

Vertebrobasilar dolichoectasia (VBD) is relatively common among patients with hemifacial spasm (HFS). Vertebral artery (VA)-associated HFS accounts for 10-30% of cases. In microvascular decompression (MVD) for these patients, mobilization of the VA and other offending vessels is challenging, often limiting exposure of the root exit zone (REZ). Glue-transposition has emerged as the primary technique to address this issue. This study aims to evaluate the outcomes and complications associated with glue-transposition through a cohort study and a comprehensive literature review. A retrospective analysis of 164 patients who underwent MVD at Shenzhen Second People's Hospital was conducted, categorizing them into VBD (14 patients) and non-VBD (150 patients) groups. Additionally, a systematic literature search was performed in PubMed up to June 2024, including clinical studies that applied the glue-transposition technique in MVD. The remission rate, complications, and surgical techniques were analyzed in detail. In our cohort, patients in the VBD group had a higher mean age and a higher prevalence of hypertension. Glue-transposition was required in 64.3% of VBD cases. Logistic regression analysis identified hypertension as significantly associated with VBD. The spasm remission rates and complication rates were comparable between VBD and non-VBD groups. The systematic review included 14 studies, of which 10 employed the one-step transposition technique, while four utilized the two-step approach. The included studies reported favorable outcomes (Cohen grade I or II) with the glue-transposition technique, ranging from 84.9 to 100%. The complication rates varied from 0 to 9.5%. Hypertension is an independent risk factor for VBD, which significantly increases the surgical complexity in MVD. Glue-transposition remains the most widely used technique for VA-associated HFS, with fibrin being the most common adhesive. We present the first experience of using cyanoacrylate as an adhesive in our cohort. Both our cohort study and literature review demonstrate that the glue-transposition technique is safe and effective.

Indexed as

Hemifacial SpasmMicrovascular Decompression SurgeryVertebrobasilar InsufficiencyAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeVertebral ArteryGlueHemifacial spasmMicrovascular decompressionVertebrobasilar dolichoectasiaVessel transposition

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.