Evidence map›Paper›PMID 40481847›Full record

Observational studyPediatric surgery international2025

Role of urodynamics in predicting fecal incontinence in spina bifida and spinal cord injury patients.

Sergio Alzate-Ricaurte, Edgar Dario Alzate Gallego, Luis De la Torre, Adria Costa-Roig, Catalina Hwang, Kelly T Harris, Duncan T Wilcox, Kyle O Rove, Andrea Bischoff

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Urogenital dysfunction in neurological diseases.Nature reviews. Neurology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sergio Alzate-RicaurteInternational Center for Colorectal and Urogenital Care, Department of Pediatric Surgery, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Edgar Dario Alzate GallegoInternational Center for Colorectal and Urogenital Care, Department of Pediatric Surgery, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Luis De la TorreInternational Center for Colorectal and Urogenital Care, Department of Pediatric Surgery, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Adria Costa-RoigInternational Center for Colorectal and Urogenital Care, Department of Pediatric Surgery, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Catalina HwangDepartment of Pediatric Urology, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Kelly T HarrisDepartment of Pediatric Urology, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Duncan T WilcoxDepartment of Pediatric Urology, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Kyle O RoveDepartment of Pediatric Urology, Children's Hospital Colorado, Aurora, CO, 80045, USA.
Andrea BischoffInternational Center for Colorectal and Urogenital Care, Department of Pediatric Surgery, Children's Hospital Colorado, Aurora, CO, 80045, USA. Andrea.Bischoff@childrenscolorado.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSpina bifida fecal incontinence (FI) rates reach 65%. Spinal cord injuries display 63% rates. Previously, we identified wheelchair use, VP shunt presence, and urinary incontinence as predictors of bowel control. Bowel control can be predicted in anorectal malformations, predictions for patients with spina bifida or spinal cord injuries have not been established.

methodsSingle-center, retrospective, observational study including patients 4 years or older at last follow-up, seen at Children's Hospital Colorado multidisciplinary spina bifida and spinal cord injury clinic, September 2020 to January 2023.

resultsFI was seen in 73% of patients. FI patients had higher end-fill pressures (EFP) (median 25 vs. 20 cmH2O), lower leak point pressures (mean 42.55 vs. 50.74 cmH2O). Analysis of 142 children younger than four, found; greater filling pressure changes (median 20 vs. 15 cmH2O), post-void residual volumes (median 20 vs. 5 ml), lower leak point pressures (mean 43.0 vs. 52.85 cmH2O). On multiple logistic regression wheelchair users (OR 2.71) and EFP greater than 24.5 cmH2O (OR 2.71) had increased odds for FI.

conclusionsBefore age 4 urodynamics are useful to predict FI in spina bifida and spinal cord injury patients. A cutoff of 24.5 cmH2O in EFP is the best predictor in urodynamics.

Indexed as

Fecal IncontinenceSpinal Cord InjuriesSpinal DysraphismUrodynamicsAdolescentChildChild, PreschoolFemaleHumansMaleRetrospective StudiesBowel managementClinical decision rulesFecal incontinenceSpina bifidaSpinal cord injuryUrodynamics

Identifiers

PMID40481847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.