Evidence map›Paper›PMID 40481776›Full record

ArticleClinical oral implants research2025

Comparison of AI-Powered Tools for CBCT-Based Mandibular Incisive Canal Segmentation: A Validation Study.

Maria Fernanda Silva da Andrade-Bortoletto, Thanatchaporn Jindanil, Rocharles Cavalcante Fontenele, Reinhilde Jacobs, Deborah Queiroz Freitas

Abstract readValidation StudyComparative Study
In one paragraph

Article in Clinical oral implants research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria Fernanda Silva da Andrade-BortolettoDepartment of Oral Diagnosis, Area of Dental Radiology, Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.ORCID 0000-0003-2300-3143
Thanatchaporn JindanilOMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU Leuven, Leuven, Belgium.ORCID 0009-0004-2724-650X
Rocharles Cavalcante FonteneleOMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU Leuven, Leuven, Belgium.ORCID 0000-0002-6426-9768
Reinhilde JacobsOMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU Leuven, Leuven, Belgium.ORCID 0000-0002-3461-0363
Deborah Queiroz FreitasDepartment of Oral Diagnosis, Area of Dental Radiology, Piracicaba Dental School, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil.ORCID 0000-0002-1425-5966

Funding

Agentschap Innoveren en OndernemenConselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
6 · The paper itself

Abstract

objectiveIdentification of the mandibular incisive canal (MIC) prior to anterior implant placement is often challenging. The present study aimed to validate an enhanced artificial intelligence (AI)-driven model dedicated to automated segmentation of MIC on cone beam computed tomography (CBCT) scans and to compare its accuracy and time efficiency with simultaneous segmentation of both mandibular canal (MC) and MIC by either human experts or a previously trained AI model. MATERIALS AND

methodsAn enhanced AI model was developed based on 100 CBCT scans using expert-optimized MIC segmentation within the Virtual Patient Creator platform. The performance of the enhanced AI model was tested against human experts and a previously trained AI model using another 40 CBCT scans. Performance metrics included intersection over union (IoU), dice similarity coefficient (DSC), recall, precision, accuracy, and root mean square error (RSME). Time efficiency was also evaluated.

resultsThe enhanced AI model had IoU of 93%, DSC of 93%, recall of 94%, precision of 93%, accuracy of 99%, and RMSE of 0.23 mm. These values were significantly higher than those of the previously trained AI model for all metrics, and for manual segmentation for IoU, DSC, recall, and accuracy (p < 0.0001). The enhanced AI model demonstrated significant time efficiency, completing segmentation in 17.6 s (125 times faster than manual segmentation) (p < 0.0001).

conclusionThe enhanced AI model proved to allow a unique and accurate automated MIC segmentation with high accuracy and time efficiency. Besides, its performance was superior to human expert segmentation and a previously trained AI model segmentation.

Indexed as

Artificial IntelligenceCone-Beam Computed TomographyMandibleHumansartificial intelligencecone beam computed tomographydental implantimage segmentationmandiblemandibular canal

Identifiers

PMID40481776
PMCPMC12423572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.