ArticleJournal of nanobiotechnology2025
Zinc-doped curcumin carbon dots promote infected wound healing with photodynamic via the VEGF signaling pathway.
Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Curcumin Loaded ZIF 8 Nanomaterials Ameliorate Porcine Endometritis Like Lesions in a Mouse Model via Regulating Macrophage Polarization and Antibacterial Activity.Animals : an open access journal from MDPI · 2026Article
- Iron, Copper, and Zinc Dyshomeostasis in Cardiovascular and Cerebrovascular Diseases: Redox Mechanisms, Evidence Levels, and Translational Prospects.International journal of molecular sciences · 2026Review
- A Curcumin-Loaded Liposomal Photodynamic Nanosystem for Effective Treatment of Bacterial Wound Infections.Pharmaceutics · 2026Article
- Programming the Diabetic-Infected Wound Microenvironment With a Smart Hydrogel for Ordered Healing Cascade Restoration.Advanced healthcare materials · 2026Article
- Wound Healing Potential of Multifunctional Nanomaterials: Mechanism, Future Prospects, and Challenges.Pharmaceutics · 2026Review
- Promoting skin regeneration: research progress on hydrogel wound dressings related to scarless healing.Journal of Zhejiang University. Science. B · 2026Review
- Adaptive Quantum Dot Biointerfaces for Precision Wound Repair.Nanomaterials (Basel, Switzerland) · 2026Review
- Phase-engineered MoSJournal of nanobiotechnology · 2026Article
- Reactive oxygen species in skin diseases: pathogenic mechanisms and nanomaterial-based therapeutic strategies.Frontiers in bioengineering and biotechnology · 2026Review
- Coordination-based nanocomposite hydrogel promotes tissue regeneration under infection-compromised conditions.Regenerative biomaterials · 2026Article
- ZIF-8 Hydrogel-Mediated Regulation of Macrophage Phenotype Accelerates Frostbite Wound Healing.Biomedicines · 2025Article
- The Role of Carbon Dots in Regulating the Periodontal Immune Microenvironment: Progress and Perspectives.International journal of molecular sciences · 2025Review
- Synergistic integration of extracellular vesicles and metal-organic frameworks: unlocking new opportunities in disease diagnosis and therapy.Theranostics · 2025Review
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Authors and funding
13 authors.
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Abstract
Management of bacterial infected wounds remains challenging due to the open, susceptibility to infection and delayed healing characteristics of damaged wounds, and there is an urgent need for non-antibiotic-based wound healing strategies. Here, we describe zinc-doped curcumin carbon dots (CCDs) as a novel nanoscale photosensitizer, which was applied in photodynamic therapy (PDT) to promote infected wound healing by modulating various cellular functions. The PDT generation of reactive oxygen species (ROS) effectively inactivates the source of infection without drug resistance, effectively inhibiting the propagation of bacteria and the spread of inflammation in the wound. In addition, CCDs have the ability to promote cell proliferation and extension, accelerate blood vessel formation and collagen deposition, and significantly improve wound healing efficiency by modulating the VEGF signaling pathway. These features create a favorable environment for skin regeneration and synergistically accelerate infected wound healing. We believe it has great potential to address antibiotic misuse and effectively manage infected wounds.
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Registered trials
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