Evidence map›Paper›PMID 40481450›Full record

ArticleBMC oral health2025

Bactericidal effect of plasma-activated water generated by a novel super-potable plasma device as a novel antibacterial method: an in vitro study.

Yinglong Li, Yu Liu, Xin Yu, Fang Zhang, Ruonan Ma, RuiXue Wang, Zuomin Wang

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. CarbopolGels (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yinglong LiDepartment of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongti South Road, Chaoyang District, Beijing, 100020, China.
Yu LiuDepartment of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongti South Road, Chaoyang District, Beijing, 100020, China.
Xin YuDepartment of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongti South Road, Chaoyang District, Beijing, 100020, China.
Fang ZhangDepartment of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongti South Road, Chaoyang District, Beijing, 100020, China.
Ruonan MaZhengzhou Research Base, National Key Laboratory of Cotton Bio-Breeding and Integrated Utilization, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450052, China.
RuiXue WangCollege of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing, 100029, China. wrx@mail.buct.edu.cn.
Zuomin WangDepartment of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gongti South Road, Chaoyang District, Beijing, 100020, China. wzuomin@sina.cn.

Funding

Beijing Nova Programme Interdisciplinary Cooperation Project 20230484449R&D Program of Beijing Municipal Education Commission KM202410025013
6 · The paper itself

Abstract

backgroundA continuous risk from bacterial infection poses a major environmental and public health challenge. As an emerging strategy for inhibiting bacterial infections, plasma-activated water (PAW) has proved highly effective, environment-friendly, and non-drug resistant to many bacteria. However, the plasma device is too big and requires specialists to operate, which inevitably limits its real-life application. It has been confirmed that the bactericidal effect of traditional PAW would be significantly reduced in the organic-rich environments. To better resolve the limitations, a novel super-portable plasma device was applied, and the low concentration of H

methodsA super-portable plasma device, weighing only 1 kg, was applied to generate PAW. Staphylococcus aureus (S. aureus), Escherichia coli (E. coli) and Porphyromonas gingivalis (P. gingivalis) were selected as the test bacteria. Colony-forming units (CFU) counting and bactericidal rate were employed to evaluate the bactericidal effect of PAW. Optical emission spectroscopy (OES) was used to identify the major reactive species in PAW. Different concentration of H

resultsThe 20 mL of PAW generated by the novel super-portable plasma device achieved the bactericidal rate of 98.94% against S. aureus (t = 10 min) and 99.66% (t = 20 min). When the PAW was prepared with a volume of 20 mL, activation times of 6 min and 8 min, and the treatment time was 30 min, the bactericidal rates all exceeded 98% against P. gingivalis. The addition of 0.1% H

conclusionsThe PAW generated by the novel super-portable plasma device exhibited an excellent bactericidal effect. The addition of low concentrations of H

Indexed as

Anti-Bacterial AgentsPlasma GasesWaterAnimalsColony Count, MicrobialEscherichia coliFibroblastsHumansHydrogen-Ion ConcentrationHydrogen PeroxideIn Vitro TechniquesPorphyromonas gingivalisStaphylococcus aureusAnti-Bacterial AgentsHydrogen PeroxidePlasma GasesWaterAntibacterial effectH2O2InfectionPlasma-activated waterSuper-portable plasma device

Identifiers

PMID40481450
PMCPMC12144717

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.