Evidence map›Paper›PMID 40481431›Full record

ArticleBMC public health2025

Exploratory analysis of the economically justifiable price of reslizumab for asthma severe in Colombia.

Jefferson Antonio Buendía, Andres Felipe Zuluaga

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jefferson Antonio BuendíaDepartamento de Farmacología y Toxicología, Facultad de Medicina, Grupo de Investigación en Farmacología y Toxicología, Universidad de Antioquia, Carrera 51D #62-29, Medellín, Colombia. jefferson.buendia@gmail.com.
Andres Felipe ZuluagaDepartamento de Farmacología y Toxicología, Facultad de Medicina, Grupo de Investigación en Farmacología y Toxicología, Universidad de Antioquia, Carrera 51D #62-29, Medellín, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAsthma severe imposes important economic burden for health systems, especially with the incorporation of new drugs. Recently, reslizumab has been approved to prevent exacerbations in patients with eosinophilic asthma. This study evaluates the price at which reslizumab would be considered economically justified for patients with severe asthma in Colombia. MATERIALS AND

methodsA model was developed using the microsimulation to estimate the quality-adjusted costs and life years of two interventions: reslizumab versus not applying standard treatment without reslizumab. This analysis was made during a time horizon of 50 year and from a third payer perspective.

resultsBased on thresholds of U$4828, U$ 5128, and U$19 992 per QALY evaluated in this study, we established economically justifiable drug acquisition prices at each WTP were U$ 106, U$ 165, and U$ 349 per dose of reslizumab. Reslizumab not was cost-effective using a WTP of U$4828, U$ 5128 and U$19 992 per QALY.

conclusionThe economically justifiable cost for reslizumab in Colombia is between U106 to U$349per dose, depending on the WTP used to decide its implementation. This result should encourage more studies in the region that optimize decision-making processes when incorporating this drug into the health plans of each country.

Indexed as

Anti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedAsthmaColombiaCost-Benefit AnalysisHumansQuality-Adjusted Life YearsSeverity of Illness IndexAnti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedreslizumabAsthmaColombiaCostPriceReslizumab

Identifiers

PMID40481431
PMCPMC12143088

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.