Evidence map›Paper›PMID 40481427›Full record

ArticleBMC microbiology2025

High throughput screening for human disease associated-pathogens and antimicrobial resistance genes in migratory birds at ten habitat sites in China.

Lan Wang, Ru Jia, Rufei Ma, Jie Li, Shanrui Wu, Yeshun Fan, Dan Zhao, Dianfeng Chu, Yihua Wang, Guogang Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lan WangDepartment of Microbial Surveillance and Biosafety, School of Public Health, Qingdao University, Qingdao, Shandong, China.
Ru JiaKey Laboratory of Biodiversity Conservation of National Forestry and Grassland Administration, Ecology and Nature Conservation Institute, Chinese Academy of Forestry, Beijing, China.
Rufei MaDepartment of Microbial Surveillance and Biosafety, School of Public Health, Qingdao University, Qingdao, Shandong, China.
Jie LiDepartment of Microbial Surveillance and Biosafety, School of Public Health, Qingdao University, Qingdao, Shandong, China.
Shanrui WuDepartment of Microbial Surveillance and Biosafety, School of Public Health, Qingdao University, Qingdao, Shandong, China.
Yeshun FanDepartment of Microbial Surveillance and Biosafety, School of Public Health, Qingdao University, Qingdao, Shandong, China.
Dan ZhaoDepartment of Microbial Surveillance and Biosafety, School of Public Health, Qingdao University, Qingdao, Shandong, China.
Dianfeng ChuYebio BioEngineering Co. Ltd of Qingdao, Qingdao, Shandong, China.
Yihua WangKey Laboratory of Biodiversity Conservation of National Forestry and Grassland Administration, Ecology and Nature Conservation Institute, Chinese Academy of Forestry, Beijing, China.
Guogang ZhangKey Laboratory of Biodiversity Conservation of National Forestry and Grassland Administration, Ecology and Nature Conservation Institute, Chinese Academy of Forestry, Beijing, China.
Jie LiuDepartment of Microbial Surveillance and Biosafety, School of Public Health, Qingdao University, Qingdao, Shandong, China. jl5yj@qdu.edu.cn.

Funding

National Key Research and Development Program of China 2021YFC0863400National Natural Science Foundation of China 32070530State Key Laboratory of Veterinary Public Health and Safety 2024SKLVPHS06
6 · The paper itself

Abstract

backgroundMigratory birds have been found to carry and spread pathogens, contaminating the environment and causing diseases in humans and other animals. To our knowledge, there hasn't been any systematic targeted screening for known pathogens in migratory birds. In the current study, customized real time PCR based TaqMan Array Cards (TAC) were used to detect 99 human disease related pathogens and 20 antimicrobial resistance (AMR) genes in migratory birds at 10 habitat sites in China.

resultsThe results showed that 30.5% (107/351) of migratory birds carried at least one of 14 pathogens. The most prevalent pathogens included Aeromonas, Plasmodium, Cryptosporidium, Giardia lamblia, enteropathogenic Escherichia coli (EPEC), Campylobacter jejuni/coli, and Rickettsia. Their distribution demonstrated certain host or region specificity. Anseriformes carried higher rate of pathogens (39.1%, 72/184) than Charadriiformes (23.2%, 33/142, p < 0.05). The overall pathogen detection rate was the highest in Hubei (87.1%, 27/31), possessing exclusively Anser. The pathogen quantities were estimated to be 10

conclusionsUsing such a multi-target detection and quantification platform, this study evaluated the potential role of migratory birds as reservoirs or vectors for a broad range of pathogens and AMR genes in the environment, indicating their capacity to transmit zoonotic diseases. These might provide evidence for implementation of targeted intervention with a one health approach.

Indexed as

BacteriaBird DiseasesBirdsHigh-Throughput Screening AssaysAnimal MigrationAnimalsChinaDrug Resistance, BacterialEcosystemHumansAntimicrobial resistanceMigratory birdsPathogenSurveillanceTaqMan Array Card

Identifiers

PMID40481427
PMCPMC12143040

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.