Evidence map›Paper›PMID 40481379›Full record

ArticleInternational journal of clinical oncology2025

Percutaneous cryoablation versus robot-assisted partial nephrectomy for small renal cell carcinoma: a retrospective cost analysis at Japanese single-institution.

Mayu Uka, Toshihiro Iguchi, Kensuke Bekku, Tomoaki Yamanoi, Toshiharu Mitsuhashi, Hideo Gobara, Noriyuki Umakoshi, Takahiro Kawabata, Koji Tomita, Yusuke Matsui and 2 more

Abstract readComparative Study
In one paragraph

Article in International journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mayu UkaDepartment of Radiology, Okayama University Hospital, Okayama, Japan. mayuuka3@gmail.com.ORCID http://orcid.org/0000-0002-8355-1961
Toshihiro IguchiDepartment of Radiology, Okayama University Hospital, Okayama, Japan.
Kensuke BekkuDepartment of Urology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Tomoaki YamanoiDepartment of Urology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Toshiharu MitsuhashiCenter for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan.
Hideo GobaraDivision of Medical Informatics, Okayama University Hospital, Okayama, Japan.
Noriyuki UmakoshiDepartment of Radiology, Okayama University Hospital, Okayama, Japan.
Takahiro KawabataDepartment of Radiology, Okayama University Hospital, Okayama, Japan.
Koji TomitaDepartment of Radiology, Okayama University Hospital, Okayama, Japan.
Yusuke MatsuiDepartment of Radiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Motoo ArakiDepartment of Urology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
Takao HirakiDepartment of Radiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNo direct cost comparison has been conducted between percutaneous cryoablation (PCA) and robot-assisted partial nephrectomy (RAPN) for clinical T1a renal cell carcinoma (RCC) in Japan. This study aimed to compare their costs.

methodsWe retrospectively analyzed data from 212 PCAs (including 155 with transcatheter arterial embolization) and 119 RAPN cases performed between December 2017 and May 2022.

resultsPCA patients were older with higher American Society of Anesthesiologists scores, Charlson Comorbidity Index, and history of previous RCC treatment, cardiovascular disease, and antithrombotic drug use than RAPN patients. PCA was associated with a significantly shorter procedure time and hospitalization duration with fewer major complications than those associated with RAPN. While PCA incurred a slightly lower total cost (1,123,000 vs. 1,155,000 yen), it had a significantly higher procedural cost (739,000 vs. 693,000 yen) and markedly worse total (- 93,000 vs. 249,000 yen) and procedural income-expenditure balance (- 189,000 vs. 231,000 yen) than those of RAPN. After statistical adjustment, PCA demonstrated significantly higher total (difference: 114,000 yen) and procedural costs (difference: 72,000 yen), alongside significantly worse total (difference: - 358,000 yen) and procedural income-expenditure balances (difference: - 439,000 yen). The incremental cost-effectiveness ratio was more favorable for PCA than for RAPN.

conclusionFor high- risk patients, PCA demonstrated a safer option with shorter hospitalization duration than those of RAPN. Although PCA was more cost-effective, its higher procedural cost and unfavorable income-expenditure balance require careful evaluation, especially for large tumors that require three or more needles.

Indexed as

Carcinoma, Renal CellCryosurgeryKidney NeoplasmsNephrectomyRobotic Surgical ProceduresAgedAged, 80 and overCost-Benefit AnalysisCosts and Cost AnalysisFemaleHumansJapanMaleMiddle AgedRetrospective StudiesCostCost effectivenessCryoablationRenal cancerRobot-assisted partial nephrectomy

Identifiers

PMID40481379
PMCPMC12296765

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.