Evidence map›Paper›PMID 40481311›Full record

ArticleCardiovascular and interventional radiology2025

Impact of Thyroid Arterial Embolization on Clinical and Biochemical Outcomes and Quality of Life in Patients with Nodular and Multinodular Goiter.

Resham Singh, Niraj Nirmal Pandey, Sanjeev Kumar, Om Prakash Prajapati, Kapil Sikka, Priya Jagia

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Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Resham Singh *Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.
Niraj Nirmal Pandey *Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.
Sanjeev KumarDepartment of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India. sanjeevradio@gmail.com.
Om Prakash PrajapatiDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, 110029, India.
Kapil SikkaDepartment of Otorhinolaryngology and Head-Neck Surgery, All India Institute of Medical Sciences, New Delhi, 110029, India.
Priya JagiaDepartment of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the safety and efficacy of thyroid arterial embolization (TAE) and its impact on clinical outcomes and quality of life (QoL) in patients with nodular and multinodular goiter (NG/ MNG). MATERIALS AND

methodsThe study included 20 patients with NG/ MNG (16 women, 4 men; mean age, 37 years) who underwent TAE using polyvinyl alcohol (PVA) particles (350-500 μm) between January 2022 and December 2023. Clinical, radiological and quality of life (QoL) assessment (thyPRO-39 questionnaire) were performed at baseline and 6 months post-procedure. Biochemical evaluation with thyroid function tests were done at 1 week, 1 month, 3 months and 6 months post-procedure.

resultsOf 20 patients, 16 had solitary thyroid nodules (STN), while 4 had multinodular goiter (MNG). Three patients had non-Graves hyperthyroidism, while the remainder were euthyroid. Technical success was achieved in all patients. 35 out of 82 interrogated thyroid arteries were seen supplying the nodules and were successfully embolized using PVA particles. At 6 months follow-up, no major complications were reported. Minor complications, including neck pain (60%), fever (20%), toothache (5%) and arm pain (5%) were seen and responded well to conservative management. The median volume of STN/dominant nodule decreased by 63.7%, from 27.5 ml (13.7-59) to 10 ml (7-17.0) (p < 0.001). Goiter score decreased from 40 (34-78.5) to 17.5 (12.5-31.5), hyperthyroid score from 15.5 (10.5-38.5) to 8 (2-13), cosmetic/ appearance score from 43 (28-51) to 1 (1-21), composite score from 26.1 (21.5-40.9) to 17.6 (14.7-26.1), and QoL score from 25 (25-50) to 0 (0-25); all changes were statistically significant (p < 0.001).

conclusionTAE is a safe and effective treatment option in the non-surgical management of benign NG/ MNG, significantly improving these patients' clinical outcome and having a favourable impact on quality of life.

Indexed as

Embolization, TherapeuticGoiter, NodularQuality of LifeThyroid GlandAdultFemaleHumansMaleMiddle AgedPolyvinyl AlcoholThyroid Function TestsTreatment OutcomePolyvinyl AlcoholInterventional radiologyQuality of lifeThyroid artery embolizationThyroid nodules

Identifiers

PMID40481311

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