Evidence map›Paper›PMID 40481286›Full record

Trial reportMolecular and cellular biochemistry2025

A randomized controlled trial on the impact of anesthetic agents on renal function in cardiac surgery with cardiopulmonary bypass.

Teng Fan, Zhili Zhao, Jun Liu, Wenke Ma, Jianmin Tian, Guifang Ma

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Molecular and cellular biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Teng FanThe First Affiliated Hospital of Xinxiang Medical University, Henan, China.
Zhili ZhaoThe First Affiliated Hospital of Xinxiang Medical University, Henan, China.
Jun LiuThe First Affiliated Hospital of Xinxiang Medical University, Henan, China. junliu98@outlook.com.
Wenke MaThe First Affiliated Hospital of Xinxiang Medical University, Henan, China.
Jianmin TianThe First Affiliated Hospital of Xinxiang Medical University, Henan, China.
Guifang MaThe First Affiliated Hospital of Xinxiang Medical University, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is a frequent and severe problem following heart surgery, particularly in procedures involving cardiopulmonary bypass (CPB). This research investigates the Randomized Controlled Trial (RCT) on the impact of agents of anesthetic on renal function in patients receiving elective cardiac surgery and CPB, comparing propofol-based and volatile anesthetic-based regimens. A sum of 61 patients was randomly assigned into two regions: one receiving a propofol-based regimen and the other, a volatile anesthetic regimen, both combined with opioid analgesia. Renal function was assessed preoperatively and postoperatively at 24 and 48 h using serum creatinine and cystatin C levels. Perioperative inflammatory markers were deliberate to evaluate inflammation-mediated renal impairment multivariate logistic regression identified risk factors for AKI, and independent t-tests compared renal function parameters between regimens. Patients receiving propofol exhibited significantly lower rates of AKI (

Indexed as

Acute Kidney InjuryAnestheticsAnesthetics, IntravenousCardiac Surgical ProceduresCardiopulmonary BypassKidneyPropofolAgedCystatin CFemaleHumansKidney Function TestsMaleMiddle AgedAnestheticsAnesthetics, IntravenousCystatin CPropofolAcute kidney injury (AKI)Anesthetic agentsCardiac surgeryCardiopulmonary bypass (CPB)Renal functionVolatile anesthetics

Identifiers

PMID40481286

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.