Evidence map›Paper›PMID 40481189›Full record

Reviewnpj antimicrobials and resistance2025

A review of natural products as a source of next-generation drugs against apicomplexan parasites.

Emma Y Mao, Stephen W Page, Brad E Sleebs, Maria R Gancheva, Danny W Wilson

Abstract readReview
In one paragraph

Review in npj antimicrobials and resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Quercetin ReducesInternational journal of molecular sciences · 2026
    Article
  3. Bio-guided identification of novel antiparasitic natural products from Gardenia imperialis K. Schum (Rubiaceae).Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emma Y MaoResearch Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia. emma.mao@adelaide.edu.au.
Stephen W PageNeoculi Pty Ltd., Burwood, Victoria, Australia.
Brad E SleebsWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.
Maria R GanchevaResearch Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia.
Danny W WilsonResearch Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia. danny.wilson@adelaide.edu.au.

Funding

Australian Research Council Industrial Transformation Training Centre IC220100050Hospital Research Foundation Fellowship 2019/41-83100National Health and Medical Research Council of Australia 1135421National Health and Medical Research Council of Australia 1143974
6 · The paper itself

Abstract

Despite the substantial global health and economic burden of apicomplexan parasites in humans and livestock, treatment options remain limited. Natural products have long played an important role in combating these diseases, offering diverse chemical structures and bioactive compounds. This review summarises past and present natural-product-based therapies for six economically significant apicomplexans and explores the potential of revisiting natural products as a source of next-generation treatments.

Identifiers

PMID40481189
PMCPMC12144137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.