Evidence map›Paper›PMID 40481108›Full record

Trial reportScientific reports2025

The effect of pericapsular nerve group block and lateral femoral cutaneous nerve block on postoperative recovery after hip arthroplasty.

Yuan Tian, Qianqian Lu, Yuxin Yuan, Zhouting Hu, Wangyu Li, Kai Li

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07771829 (Comparison of Ultrasound-Guided QLESP Block Versus Pericapsular Nerve Group Block Combined With Lateral Femoral Cutaneous Nerve Block on Postoperative Analgesia and Functional Recovery in Total Hip Arthroplasty), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07771829 narecruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Ultrasound-Guided QLESP Block Versus Pericapsular Nerve Group Block Combined With Lateral Femoral Cutaneous Nerve Block on Postoperative Analgesia and Functional Recovery in Total Hip Arthroplasty: A Randomized Controlled Trial

TypeinterventionalSponsorHuazhong University of Science and TechnologyRan2026 to 2027Enrolled136ConditionsPain Management, Arthroplasty Total Hip ReplacementArmsQLESP Block, PENG+LFCN Block, ropivacaine
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan TianDepartment of Anesthesiology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250033, Shandong Province, China.
Qianqian LuOperation Room, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, China.
Yuxin YuanDepartment of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, China.
Zhouting HuDepartment of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, China.
Wangyu LiDepartment of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, China.
Kai LiDepartment of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, China. likai@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Total hip arthroplasty can cause moderate and severe pain that can have a profound impact during postoperative rehabilitation. Regional nerve block is recommended for anesthesia and analgesia during hip surgery. In particular, the iliac fascia space block of the inguinal ligament is a widely used technique in clinical practice that can block the femoral nerve trunk, obturator nerve trunk, and lateral femoral cutaneous nerve simultaneously. This study aimed to compare the effect of supra-inguinal fascia iliaca compartment block (S-FICB) to a combination of pericapsular nerve group block (PNGB) and lateral femoral cutaneous nerve block (LFCNB) on block range and analgesia as well as motor function of patients with total hip arthroplasty. Sixty patients undergoing total hip arthroplasty through posterolateral approach were randomly divided into two groups with 30 patients each. After complete awakening from general anesthesia, patients received ultrasound-guided S-FICB with 40 mL 0.4% ropivacaine (group S) or 20 mL 0.4% ropivacaine PNGB combined with 3 mL 0.4% ropivacaine LFCNB (PH group). We used the Numerical Rating Scale and cumulative dosage of sufentanil to grade pain during the first 48 h. Quadriceps femoris muscle and adductor muscle strength, range of sensory block, length of stay, and complications were also recorded. No significant differences were found in analgesic indicators of both groups (P>0.05). The Numerical Rating Scale scores of resting pain at each time point after the blockage were significantly lower than those before the blockage (P<0.05). However, the PH group had significantly less incidence of analgesia sensation in the anterior and medial side of the thigh (P < 0.05), and less incidence of quadriceps and adductor weakness (P<0.05) at 1 h and 6 h after the blockage compared to that in group S. Compared to S-FICB, the combination of PNGB and LFCNB provided equivalent analgesic effect and significantly lowered the risk of numbness and muscle weakness of the thigh, which is more conducive to early postoperative exercise and rehabilitation .This combination can be used as a new option in multimodal analgesia after total hip arthroplasty.Trial registration: Chinese Clinical Trial Registry (no. ChiCTR2200055963, date of registration 29/01/2022).

Indexed as

Arthroplasty, Replacement, HipFemoral NerveNerve BlockPostoperative PainAgedFemaleHumansMaleMiddle AgedRopivacaineRopivacaineAnalgesiaMuscle weaknessNumbnessRegional nerve block

Identifiers

PMID40481108
PMCPMC12144274

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.