Evidence map›Paper›PMID 40481078›Full record

ArticleScientific reports2025

Biomechanics characterization of an implantable ultrathin intracortical electrode through finite element method.

Linsen Peng, Longchun Wang, Shuhui Wu, Mingcheng Gu, Shang Deng, Jingquan Liu, Cheng-Kung Cheng, Xiaohong Sui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linsen PengSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Longchun WangNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Shuhui WuSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Mingcheng GuSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Shang DengSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Jingquan LiuNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Cheng-Kung ChengSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. ckcheng2020@sjtu.edu.cn.
Xiaohong SuiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. suixhong@sjtu.edu.cn.

Funding

the National Natural Science Foundation of China No. 62176158the STAR Project of Shanghai Jiao Tong University WH410362603/001the STI 2030-Major Projects No. 2022ZD0208601
6 · The paper itself

Abstract

Neural electrodes are widely used in brain-computer interfaces and neuroprosthesis for the treatment of various neurological disorders. However, as components that come into direct contact with neural tissue, implanted neural electrodes could cause mechanical damage during surgical insertions or while inside the brain. Thus, accurately and timely assessing this damage was vital for chronic implantation, which posed a significant challenge. This study aimed to evaluate the biomechanical effects and clinical application risks of a polyimide-based ultrathin flexible intracortical microelectrode through the finite element method (FEM). It analyzed the electrode-brain biomechanical effects during the electrode's insertion process and under steady-state acceleration with the electrode inside the brain. Furthermore, the study examined the impact of factors including implantation depth (ranging from 5 to 5000 μm), cortical thickness (0.5 mm, 2.5 mm, and 4.5 mm), step displacement (from 1 to 5 μm) during insertion, and acceleration direction (vertical and horizontal) on the electrode's biomechanical effects. The primary findings showed that the 98th percentile Von Mises Strain (ε

Indexed as

Electrodes, ImplantedBiomechanical PhenomenaBrainBrain-Computer InterfacesFinite Element AnalysisHumansMicroelectrodesStress, MechanicalBiomechanicsElectrode insertion surgeryFinite element methodFlexible microelectrode

Identifiers

PMID40481078
PMCPMC12144109

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.