Trial reportScientific reports2025
Randomised active controlled trial examining effects of aerobic exercise, cognitive and music interventions on depression, balance and mobility in schizophrenia.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Schizophrenia significantly impairs daily functioning, requiring innovative, cost-effective treatments beyond standard antipsychotics, and cognitive interventions. This study examined the individual and combined effects of cognitive, music, and aerobic exercise interventions on depression, balance, and mobility in patients with schizophrenia and severe depression. Eighty-four male patients with schizophrenia and severe depression from an inpatient psychiatric centre participated in a 12-week, single-blind, randomised active-controlled trial. Participants were systematically assigned to one of seven equal groups (n = 12 each): aerobic exercise (AerG), cognitive rehabilitation/treatment-as-usual (CogG), music intervention (MusG), aerobic exercise + music intervention (A&MG), aerobic exercise + cognitive intervention (A&CG), cognitive intervention + music intervention (C&MG), and a comprehensive combination of all three modalities (ACMG). Each intervention was delivered over 60 min, three times weekly for 12 weeks. The study employed the Beck Depression Inventory Short Form, Stork Balance Test, and modified Timed Up and Go Test to assess improvements in depression, balance, and mobility. Statistical analyses were conducted using paired t-tests for within-group comparisons and ANCOVA with Bonferroni post hoc tests for between-group differences, with significance set at p ≤ 0.05. Results showed significant improvements in depression, balance, and mobility across all treatment groups. The CogG group outperformed both AerG and MusG in all outcomes, establishing it as the gold-standard comparator. A&CG yielded greater benefits than other single or dual-modality groups, while the multimodal ACMG group demonstrated the most substantial improvements across all measures. These findings highlight the practical value of incorporating multimodal interventions into standard care to improve both mental health and physical function, offering a scalable, cost-effective approach to addressing the diverse needs of this population of patients with schizophrenia and severe depression. Implementing such interventions in psychiatric care settings could lead to more comprehensive and effective treatment strategies for improving patient outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.