Evidence map›Paper›PMID 40480759›Full record

ArticleJACC. Case reports2025

Pregnancy and Delivery Care for a Patient With a HeartMate 3.

Sara I Jones, Heather Acuff, Ryan Best, Yen-Yen Gee, Sarah C Snow, Richa Agarwal, Karen Flores Rosario, Jennifer B Gilner, Jerome J Federspiel, Marie-Louise Meng

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara I JonesDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina, USA. Electronic address: sara.jones@duke.edu.
Heather AcuffDepartment of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.
Ryan BestDepartment of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.
Yen-Yen GeeDepartment of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.
Sarah C SnowDivision of Cardiology, Duke University Hospital, Durham, North Carolina, USA.
Richa AgarwalDivision of Cardiology, Duke University Hospital, Durham, North Carolina, USA.
Karen Flores RosarioDivision of Cardiology, Duke University Hospital, Durham, North Carolina, USA.
Jennifer B GilnerDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina, USA.
Jerome J FederspielDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina, USA; Division of Hematology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Marie-Louise MengDepartment of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe limited available data on pregnancies among patients with left ventricular assist devices (LVADs) in situ shows elevated rates of maternal and fetal/neonatal morbidity and mortality. The first fully magnetically levitated device providing centrifugal continuous flow, HeartMate 3 (HM3, Abbott), is the only LVAD available in the United States since 2018 and has fewer adverse patient outcomes compared with previous devices. CASE SUMMARY: A 32-year-old G5P2113 woman became pregnant 19 months after destination-therapy HM3 LVAD placement. Uncomplicated antepartum care and a cesarean delivery at 34 weeks under neuraxial anesthesia was facilitated by our institution's pregnancy heart team. DISCUSSION: This represents the second reported HM3-supported pregnancy resulting in a live birth. Various barriers to care guided a shared anticoagulation plan, and no hemorrhagic or thrombotic complications occurred. Our intrapartum monitoring strategy facilitated a patient-centered delivery and postpartum experience while maintaining excellent patient safety.

Indexed as

anesthesiaanticoagulationcardiac assist devicescardiomyopathyheart failurepregnancy

Identifiers

PMID40480759
PMCPMC12235154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.