Evidence map›Paper›PMID 40480666›Full record

ArticleBMJ open2025

Studies on cognitive performance among older people living with HIV in eastern Europe and central Asia: a scoping review.

Esma Imerlishvili, Deborah R Gustafson, Mariam Pashalishvili, Danielle C Ompad, Mamuka Djibuti

Abstract readScoping Review
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Esma ImerlishviliIvane Javakhishvili Tbilisi State University Faculty of Medicine, Tbilisi, Georgia esma.imeri@gmail.com.ORCID http://orcid.org/0000-0002-8512-0575
Deborah R GustafsonDepartment of Neurology, SUNY Downstate Health Sciences University, New York City, Brooklyn, USA.ORCID http://orcid.org/0000-0001-9556-8560
Mariam PashalishviliIvane Javakhishvili Tbilisi State University Faculty of Medicine, Tbilisi, Georgia.
Danielle C Ompad *Department of Epidemiology, New York University School of Global Public Health, New York, New York, USA.
Mamuka Djibuti *Partnership for Research and Action for Health, Tbilisi, Georgia.ORCID http://orcid.org/0000-0002-1614-854X

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
MWCCS: Brooklyn Clinical Research SiteU01HL146202 · NHLBI · SUNY DOWNSTATE MEDICAL CENTER · PI TRACEY ELIZABETH WILSON, Jessica Eve Yager · 2019 to 2026
$23.6M
Vascular contributions to cognitive impairments and dementia (VCID) among people living with HIV in the country of GeorgiaD43TW011532 · FIC · PARTNERSHIP FOR RESEARCH/ACTION/HEALTH · PI DEHOVITZ, JACK A, DJIBUTI, MAMUKA · 2020 to 2024
$1.8M
FIC NIH HHS D43 TW011532NHLBI NIH HHS U01 HL146202NIDA NIH HHS P30 DA011041
6 · The paper itself

Abstract

backgroundDespite the growth of the population of older people living with HIV (PLWH), data on cognitive disorders among older PLWH, particularly in low- and middle-income countries, are scarce. These data are especially underrepresented in the literature from eastern Europe and central Asia (EECA).

objectivesThis scoping review aimed to describe the peer-reviewed literature on cognitive health among PLWH in the EECA region. ELIGIBILITY CRITERIA: We selected articles from peer-reviewed journals that reported on cognitive assessments or the prevalence and characteristics of cognitive disorders among adult (≥18 years) PLWH in EECA countries (Armenia, Azerbaijan, Belarus, Estonia, Georgia, Kazakhstan, Kyrgyzstan, Latvia, Lithuania, Moldova, Russia, Tajikistan, Turkmenistan, Ukraine and Uzbekistan). Studies assessing cognition among PLWH related to traumatic brain injury, brain tumours, COVID-19, meningitis, neurosyphilis and/or other central nervous system infections were excluded. SOURCE OF EVIDENCE: We searched for relevant data published up to March 2025 using four online databases (PubMed, CINAHL, Web of Science and PsycINFO). CHARTING

methodsCovidence, a web-based collaborative software platform, was used for data screening and extraction. Two independent reviewers screened abstracts and full texts, resolving disagreements through consensus. The data were extracted based on the predefined data extraction criteria.

resultsA total of 1388 peer-reviewed articles were identified; 295 articles were removed due to duplication; and 1053 and 25 articles were excluded based on the abstract/title and full-text screenings, respectively. Finally, 15 articles met the inclusion criteria. All 15 studies used different neuropsychological assessments to measure cognitive performance by domain and/or cognitive disorders among various subgroups of PLWH. One cross-sectional study focused on older populations (≥40 years old), using standardised cognitive performance assessment tests. However, it neither provided information about the prevalence estimate of cognitive disorders nor identified risk factors.

conclusionExisting literature on cognitive disorders among older PLWH in the EECA region is limited and insufficient to estimate prevalence, or identify risk factors, and ultimately develop appropriate policy addressing the needs of older PLWH in this region. This scoping review underscores the urgent need for large-scale, longitudinal studies employing standardised, culturally adapted neuropsychological batteries and adherence to rigorous reporting standards.

Indexed as

CognitionCognitive DysfunctionHIV InfectionsAgedAsia, CentralEurope, EasternHumansPrevalenceAgingHIV & AIDSInfectious disease/HIV

Identifiers

PMID40480666
PMCPMC12161406

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.