Evidence map›Paper›PMID 40480665›Full record

ArticleBMJ open2025

Evaluating impacts of improved flooring on enteric and parasitic infections in rural households in Kenya: study protocol for a cluster-randomised controlled trial.

Katherine E Halliday, Stella Kepha, Hugo Legge, Elizabeth Allen, Robert Dreibelbis, Lynne Elson, Beatrice K Kakoi, Carlos Mcharo, Sharon Muli, Jacinta Mwongeli and 10 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05914363 (Evaluating the Impact of an Improved Household Flooring Intervention on Enteric and Parasitic Infections in Rural Settings in the Counties of Bungoma and Kwale, Kenya), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05914363 nacompletednot on this map

Evaluating the Impact of an Improved Household Flooring Intervention on Enteric and Parasitic Infections in Rural Settings in the Counties of Bungoma and Kwale, Kenya

TypeinterventionalSponsorLondon School of Hygiene and Tropical MedicineRan2023 to 2024Enrolled2,200ConditionsDiarrhoeal Disease, Hookworm Infection, Ascaris Lumbricoides Infection, Trichuris InfectionArmsSealed washable floor plus behaviour change, Behaviour change intervention, Routine deworming, treatment for tungiasis
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Natural history and impact ofmedRxiv : the preprint server for health sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Katherine E HallidayDepartment of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK katherine.halliday@lshtm.ac.uk.ORCID http://orcid.org/0000-0001-5307-2823
Stella KephaEastern and Southern Africa Centre of International Parasite Control (ESACIPAC), Kenya Medical Research Institute, Nairobi, Kenya.
Hugo LeggeDepartment of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Elizabeth AllenDepartment of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Robert DreibelbisDepartment of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Lynne ElsonKenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Beatrice K KakoiDepartment of Biomechanical and Environmental Engineering, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Carlos McharoEastern and Southern Africa Centre of International Parasite Control (ESACIPAC), Kenya Medical Research Institute, Nairobi, Kenya.
Sharon MuliDisease Ecology Group, International Centre for Insect Physiology and Ecology, Nairobi, Kenya.
Jacinta MwongeliCollege of Engineering and Technology, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Doris NjomoEastern and Southern Africa Centre of International Parasite Control (ESACIPAC), Kenya Medical Research Institute, Nairobi, Kenya.
Margaret M NjorogeDisease Ecology Group, International Centre for Insect Physiology and Ecology, Nairobi, Kenya.
Victoria OchwalDisease Ecology Group, International Centre for Insect Physiology and Ecology, Nairobi, Kenya.
William E OswaldDepartment of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Martin RonoKenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Tuva K SafariDisease Ecology Group, International Centre for Insect Physiology and Ecology, Nairobi, Kenya.
Ulrike FilingerDisease Ecology Group, International Centre for Insect Physiology and Ecology, Nairobi, Kenya.
James Wambua KaluliDepartment of Biomechanical and Environmental Engineering, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Charles S MwandawiroEastern and Southern Africa Centre of International Parasite Control (ESACIPAC), Kenya Medical Research Institute, Nairobi, Kenya.
Rachel L PullanDepartment of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionEarthen floors are often damp or dusty and difficult to clean, providing an ideal environment for faecal pathogens and parasites. Observational studies have revealed associations between household flooring and health outcomes, but robust experimental evidence is scant. This study will evaluate the impact of an improved household flooring intervention on enteric infections, soil-transmitted helminth (STH) infections and tungiasis through implementation of a cluster-randomised trial in two rural settings in Kwale and Bungoma Counties, Kenya. METHODS AND ANALYSES: 440 clusters (households) across both sites are allocated to control or intervention group, in which a low-cost, sealed, washable, cement-based floor is installed in eligible buildings of the dwelling, alongside a floor-care guide provided during an induction meeting. Following baseline assessments in both groups, all individuals over 1 year receive albendazole and those infected with tungiasis receive benzyl benzoate. Primary outcomes are as follows: prevalence of enteric infections in children under 5 years assessed via stool surveys and PCR; prevalence of tungiasis infection in children 1-14 years based on clinical exam; and prevalence of STH infection in all household members over 1 year assessed via Kato-Katz. Secondary outcomes include the following: intensity of STH and tungiasis infections; prevalence of caregiver-reported gastrointestinal illness in children under 5; quality of life and well-being measures; and environmental contamination. A process evaluation investigates intervention acceptability, durability, practicality and cost. ETHICS AND DISSEMINATION: The protocol has been approved by ethics committees of The Kenya Medical Research Institute, The Kenya National Commission for Science Technology and Innovation, and The London School of Hygiene & Tropical Medicine. Following the 12-month implementation period and final assessments, control households are offered improved floors. Results will be disseminated within Kenya, to the Ministries of Health and of Lands, Public Works, Housing and Urban Development, and to subnational leadership and communities. Dissemination will also occur through publications and conference presentations. TRIAL REGISTRATION NUMBER: NCT05914363.

Indexed as

Floors and FloorcoveringsHelminthiasisIntestinal Diseases, ParasiticTungiasisAdolescentAlbendazoleChildChild, PreschoolFamily CharacteristicsFecesFemaleHumansInfantKenyaMalePrevalenceAlbendazoleEpidemiologyGastrointestinal infectionsPARASITOLOGYPublic healthRandomized Controlled Trial

Identifiers

PMID40480665
PMCPMC12161379

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.