Evidence map›Paper›PMID 40479538›Full record

ReviewChemical reviews2025

Recent Advances in the Use of Ionic Liquids and Deep Eutectic Solvents for Lignocellulosic Biorefineries and Biobased Chemical and Material Production.

Pedro Verdía Barbará, Hemant Choudhary, Pedro S Nakasu, Amir Al-Ghatta, Yinglei Han, Cynthia Hopson, Raul I Aravena, Dhirendra Kumar Mishra, Antonio Ovejero-Pérez, Blake A Simmons and 1 more

Abstract readReview
In one paragraph

Review in Chemical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pedro Verdía BarbaráDepartment of Chemical Engineering and Materials, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Hemant ChoudharyDeconstruction Division, Joint BioEnergy Institute, Emeryville, California 94608, United States.ORCID 0000-0003-2847-3080
Pedro S NakasuDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2AZ, United Kingdom.ORCID 0000-0001-5806-0856
Amir Al-GhattaDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2AZ, United Kingdom.ORCID 0000-0002-0599-1494
Yinglei HanDeconstruction Division, Joint BioEnergy Institute, Emeryville, California 94608, United States.ORCID 0000-0001-8840-0604
Cynthia HopsonDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2AZ, United Kingdom.
Raul I AravenaDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2AZ, United Kingdom.
Dhirendra Kumar MishraDeconstruction Division, Joint BioEnergy Institute, Emeryville, California 94608, United States.ORCID 0000-0002-5730-7834
Antonio Ovejero-PérezDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2AZ, United Kingdom.ORCID 0000-0001-8752-1340
Blake A SimmonsDeconstruction Division, Joint BioEnergy Institute, Emeryville, California 94608, United States.ORCID 0000-0002-1332-1810
Jason P HallettDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2AZ, United Kingdom.ORCID 0000-0003-3431-2371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biorefineries, which process biomass feedstocks into valuable (bio)products, aim to replace fossil fuel-based refineries to produce energy and chemicals, reducing environmental and health hazards, including climate change, and supporting a sustainable economy. In particular, lignocellulose-based biorefineries, utilizing the most abundant renewable feedstock on Earth, have significant potential to supply sustainable energy, chemicals and materials. Ionic liquids (ILs, organic salts with low melting temperatures) and deep eutectic solvents (DESs, mixtures with eutectic points lower than the ideal mixture) are capable of dissolving some of the key lignocellulose polymers, and even the whole biomass. Furthermore, they have intrinsic advantages over molecular solvents, including safer usage profiles and high tunability, which allow tailored physicochemical properties. Such properties provide unique opportunities for the development of new processes that could unlock the full potential of future biorefineries. Here, we review the current state of lignocellulosic biomass processing with ILs and DESs, with a specific focus on the pretreatment chemistry, process flow and products from each component; followed by discussions on sustainability assessments and technological challenges. We aim to inform the research community about the opportunities, challenges and perspectives in developing truly sustainable lignocellulose-based biorefineries.

Identifiers

PMID40479538
PMCPMC12203485

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.