Evidence map›Paper›PMID 40479512›Full record

ReviewThe Plant cell2025

Core biological principles and tools stemming from basic Arabidopsis research.

Lucia C Strader, David Edwards, Sridevi Sureshkumar, Sureshkumar Balasubramanian, Tianyuan Chen, Xinnian Dong, Mauricio S Antunes, Lili Zebluim, Patarasuda Chaisupa, R Clay Wright

Abstract readReview
In one paragraph

Review in The Plant cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lucia C StraderDepartment of Biology, Duke University, Durham, NC 27708, USA.ORCID 0000-0002-7600-7204
David EdwardsSchool of Biological Sciences, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0001-7599-6760
Sridevi SureshkumarSchool of Biological Sciences, Monash University, Clayton Campus, VIC 3800, Australia.
Sureshkumar BalasubramanianSchool of Biological Sciences, Monash University, Clayton Campus, VIC 3800, Australia.
Tianyuan ChenHoward Hughes Medical Institute, Duke University, Durham, NC 27708, USA.ORCID 0000-0003-3159-4342
Xinnian DongHoward Hughes Medical Institute, Duke University, Durham, NC 27708, USA.ORCID 0000-0002-1120-0951
Mauricio S AntunesDepartment of Biological Sciences, University of North Texas, Denton, TX 76203, USA.ORCID 0000-0002-5453-1531
Lili ZebluimBiological Systems Engineering, Virginia Tech, Blacksburg, VA 24061, USA.
Patarasuda ChaisupaBiological Systems Engineering, Virginia Tech, Blacksburg, VA 24061, USA.
R Clay WrightBiological Systems Engineering, Virginia Tech, Blacksburg, VA 24061, USA.ORCID 0000-0001-7125-3943

Funding

Understanding and Engineering Chemically Activated Ubiquitin LigasesR35GM150856 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Robert Clay Wright · 2023 to 2026
$1.5M
Ministry of Science and TechnologyNational Institute of General Medical Science of the National Institutes of Health R35GM150856NIGMS NIH HHS R35 GM150856Royal Thai Government
6 · The paper itself

Abstract

The model plant Arabidopsis thaliana has been a cornerstone of research in plant biology, contributing transformative insights into fundamental biological processes across eukaryotes. In this vignette, we explore the role of Arabidopsis in elucidating immune mechanisms, where plant studies have informed mammalian immunity and translational regulation. We discuss how Arabidopsis-driven advancements in pangenomics and repeat expansions have reshaped our understanding of genomic variability and its implications for diseases like Friedreich's ataxia. Breakthroughs in synthetic biology and bioproduction underscore the role of Arabidopsis as a testbed for engineering specialized metabolites and advancing biotechnological applications. Finally, we examine how the development of tools like auxin-inducible degradation has extended beyond plant research, providing critical methodologies to study protein function and develop novel therapeutics.

Indexed as

ArabidopsisArabidopsis ProteinsSynthetic BiologyArabidopsis Proteins

Identifiers

PMID40479512
PMCPMC12290887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.