ArticleLangenbeck's archives of surgery2025
Predicting post-hepatectomy liver failure based on future remnant liver function combined with future remnant liver volume using magnetic resonance imaging.
Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Radiomics Beyond Radiology: Literature Review on Prediction of Future Liver Remnant Volume and Function Before Hepatic Surgery.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSignificant advances have been made in image-based determinations of future remnant liver function, in attempts to better predict post-hepatectomy liver failure (PHLF). We have reported time-associated liver functional assessments using magnetic resonance imaging with liver-to-spleen signal intensity ratio increasing rate (LSRi) and LSRi of the future remnant liver region (LSRi-rem) to predict PHLF. This study aimed to investigate the predictability of PHLF by a preoperative liver function assessment index that combined LSRi-rem and future remnant liver volume (FRLV).
methodsParticipants comprised 333 patients who underwent EOB-MRI for the diagnosis of liver tumor before major hepatectomy between 2009 and 2024. LSRi-rem was evaluated by three-dimensional volumetric analysis, and the volume adjusted LSRi-rem (vaLSRi-rem) was calculated using the following formula: LSRi-rem × (FRLV / whole-liver volume). The vaLSRi-rem and clinical variables were then analyzed to assess the risk of PHLF.
resultsIn patients with vaLSRi-rem < 0.147, right hepatectomy, operation time ≥ 400 min, and estimated blood loss ≥ 1495 mL were associated with clinically relevant PHLF (P < 0.05 each) in multivariable analysis. Multivariable analysis showed the highest odds ratio (OR) for vaLSRi-rem (OR 9.12; P < 0.01). Of the 333 patients, 114 (34%) underwent portal vein embolization before major hepatectomy. The OR of vaLSRi-rem from multivariable analysis in this patient cohort was particularly high (OR 21.04; P < 0.01).
conclusionsStrong associations were identified between vaLSRi-rem and clinically relevant PHLF after major hepatectomy, particularly among portal vein embolization patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.