Evidence map›Paper›PMID 40478403›Full record

ArticleDiscover oncology2025

Causal associations between air pollution and breast cancer risk and survival: a Mendelian randomization study.

Wenhuan Li, Yonggang Yang, Rong Xie, Xinyu Su, Pengfei Shi, Lin Chen, Bo Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenhuan Li *Department of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, Hubei, China.
Yonggang Yang *Department of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, Hubei, China.
Rong Xie *Department of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, Hubei, China.
Xinyu SuDepartment of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, Hubei, China.
Pengfei ShiDepartment of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, Hubei, China.
Lin ChenWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China. linchenfz2021@163.com.
Bo HuDepartment of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, Hubei, China. HuBo_WHZhongxin201@163.com.

Funding

Natural Science Foundation of Hubei Province No. 2023AFB1023
6 · The paper itself

Abstract

backgroundAir pollution has been implicated in various health conditions, including cancer. However, the relationship between long-term exposure to air pollution and breast cancer risk, its subtypes, and survival remains unclear.

methodsThis study employed a two-sample Mendelian Randomization (MR) design to investigate the causal effects of PM

resultsMR analysis demonstrated a significant causal association between genetically predicted NO₂ and PM

conclusionsThis study provides evidence of a causal link between long-term exposure to NO₂ and PM

Indexed as

Air pollutionBreast cancerCausal relationshipMendelian randomizationSurvival

Identifiers

PMID40478403
PMCPMC12144015

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.