Evidence map›Paper›PMID 40478212›Full record

ArticleMedical and veterinary entomology2025

Extended time to maturity in Anopheles coluzzii: Implications of late egg hatch for vector control and transgene fitness.

Emmanuel C Ottih, Joe M Roberts, Toby J A Bruce, Frédéric Tripet

Abstract read
In one paragraph

Article in Medical and veterinary entomology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Age-dependent mating dynamics, body size, and sex ratio in colonisedCurrent research in parasitology & vector-borne diseases · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emmanuel C OttihCentre of Applied Entomology and Parasitology, School of Life Sciences, Keele University, Staffordshire, UK.ORCID 0009-0004-4755-610X
Joe M RobertsEntomology Group, Centre for Crop and Environmental Science, Harper Adams University, Newport, UK.ORCID 0000-0002-9576-9239
Toby J A BruceCentre of Applied Entomology and Parasitology, School of Life Sciences, Keele University, Staffordshire, UK.ORCID 0000-0002-9912-0605
Frédéric TripetSwiss Tropical and Public Health Institute, Allschwil, Switzerland.ORCID 0000-0002-7939-0712

Funding

Bill and Melinda Gates Foundation
6 · The paper itself

Abstract

Maintaining fitness is an important consideration when mosquitoes are mass-reared for the deployment of genetic interventions that are designed to suppress populations because released mosquitoes need to compete with wild-type mosquitoes. Late-hatching mosquitoes are more suitable for transportation to remote field sites. Here, we investigated the fitness of late-hatching phenotypes in Anopheles coluzzii. Selected lines of the VK strain (from Burkina Faso) were created through bidirectional selection for early and late hatching, over 20 generations. These were compared with each other and the established Mopti reference strain from Mali, reared in the lab for >16 years. Significant differences in life-history traits were found between Mopti and VK strains but few differences were found between the selected VK lines. Considering that late-hatching VK lines showed no evidence of fitness costs, our results suggest that the late selected VK lines, which start hatching after 4 days, are an alternative option for egg shipment for mass mosquito releases over the well-established Mopti that hatches within 2 days and has lower adult survival.

Indexed as

AnophelesGenetic FitnessMosquito ControlMosquito VectorsAnimalsBurkina FasoFemaleLarvaLife History TraitsMaleOvumTransgenesAnopheles coluzziibidirectional selectionearly and late hatchinggenetically modified mosquitoesMoptimosquito mass rearingphenotypesstrainsVK

Identifiers

PMID40478212
PMCPMC12586298

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.