Evidence map›Paper›PMID 40477883›Full record

ArticleHuman pathology reports2022

Hypercoagulopathy as a severe Long-term complication of post SARS-CoV-19 infection.

Xinhai R Zhang, Indu Agarwal, Jian Jing, Lin Cheng, Gladson Scaria, Mamoor Latef, Paolo Gattuso

Abstract readCase Reports
In one paragraph

Article in Human pathology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinhai R ZhangDepartment of Pathology, Rush University Medical Center, Chicago, IL 60612, USA.
Indu AgarwalDepartment of Pathology, Rush University Medical Center, Chicago, IL 60612, USA.
Jian JingDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Lin ChengDepartment of Pathology, Rush University Medical Center, Chicago, IL 60612, USA.
Gladson ScariaDepartment of Pathology, Rush University Medical Center, Chicago, IL 60612, USA.
Mamoor LatefDepartment of Pathology, Rush University Medical Center, Chicago, IL 60612, USA.
Paolo GattusoDepartment of Pathology, Rush University Medical Center, Chicago, IL 60612, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two years since the advent of the COVID-19 pandemic, it is time to discuss the long-term complications post virus infection. We are reporting three autopsy cases from patients who had COVID-19 one to six months before death. All three patients were SARS-CoV-2 negative at admission but expired shortly. At autopsy, the first patient showed subacute diffuse myocardial ischemic injury with microthrombi in pericardial small vessels, whereas the second patient showed catastrophic acute and subacute pulmonary infarctions with hemothorax leading to respiratory failure. The third patient showed subacute severe cerebral infarcts in the left middle cerebral artery region. Our findings suggest the hypercoagulopathy and subsequent vital organ damage may persist beyond the active phase of SARS-CoV-2 infection. It is essential to continue monitoring the COVID-19 patients after recovery, so as to identify those with vital organ injury in a timely manner and to take necessary steps to prevent severe consequences of COVID-19 complications.

Indexed as

AutopsyCOVID-19HypercoagulopathyLong-term complication

Identifiers

PMID40477883
PMCPMC8810306

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.