ArticleJournal of radiosurgery and SBRT2025
Convolution-based Gamma Knife planning from ICON CBCT: Three-level stepwise electron density assignment versus Hounsfield Unit curve.
Article in Journal of radiosurgery and SBRT, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aims: To assess the suitability of CBCT images for dose calculation using the convolution algorithm. Methods: A CT to electron density curve was produced for the Gamma Knife ICON CBCT scanner. A three-level stepwise curve with fixed electron densities for air, brain tissue and bone was also produced. For 10 patients, the beam on time for shots in 11 locations within the brain was calculated using each of these curves and compared to beam on times calculated using the TMR10 algorithm, and the convolution algorithm with CT images. Results: The ratios of the average beam on time for convolution versus TMR10 were 1.058, 1.216 and 1.052 for CT images, CBCT images (Hounsfield unit electron density curve) and CBCT images (three-level stepwise curve with fixed electron densities) respectively. Conclusions: Using ICON CBCT images for dose calculation can result in an underestimation of the dose compared to convolution using CT images. However, using CBCT images along with a three-level stepwise electron density curve with fixed electron densities can provide good agreement with doses calculated using convolution with CT images.
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