Evidence map›Paper›PMID 40476241›Full record

ArticleRSC advances2025

Dual modification of nickel nanoclusters for selective detection of glutathione through a competitive displacement mechanism.

Yousef A Bin Jardan, Mohamed R Elmasry, Al-Montaser Bellah H Ali, Mohamed M El-Wekil

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yousef A Bin JardanDepartment of Pharmaceutics, College of Pharmacy, King Saud University Riyadh Saudi Arabia Ybinjardan@ksu.edu.sa.
Mohamed R ElmasrySchool of Chemical Engineering, Sungkyunkwan University (SKKU) Suwon 16419 Republic of Korea.
Al-Montaser Bellah H AliDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University Assiut 71526 Egypt mohamed.elwakeel@pharm.aun.edu.eg mohamed.mohamoud@ymail.com.
Mohamed M El-WekilDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University Assiut 71526 Egypt mohamed.elwakeel@pharm.aun.edu.eg mohamed.mohamoud@ymail.com.ORCID https://orcid.org/0000-0002-1097-1148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutathione (GSH) is a vital biomolecule that plays a fundamental role in biological systems, regulating numerous cellular functions. Given its physiological significance, the development of analytical sensors capable of sensitively and selectively detecting GSH is of great importance. In this study, a novel fluorescent probe was designed for the detection of GSH in dietary supplements and human biological fluids. The probe consists of nickel nanoclusters (NiNCs) stabilized by polyethyleneimine (PEI) and dithioerythritol (DTH) (PEI/DTH@NiNCs) as dual-protecting ligands. DTH functions as both a stabilizing and reducing agent, while PEI serves as an additional stabilizer, enhancing the structural integrity and stability of the nanoclusters. The fluorescence emission of PEI/DTH@NiNCs was significantly quenched in the presence of Fe

Identifiers

PMID40476241
PMCPMC12135858

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.