Evidence map›Paper›PMID 40476160›Full record

ArticlePatient preference and adherence2025

Understanding Suboptimal Insulin Use in Type 1 and Type 2 Diabetes: A Cross-Sectional Survey of People with Diabetes.

Rachel S Newson, Esther Artime, Julie Bower, Erik Spaepen, Birong Liao, Indranil Bhattacharya, Tadej Battelino

Abstract read
In one paragraph

Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Perceptions of Suboptimal Insulin Dosing from People with Diabetes and Healthcare Professionals in Germany.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rachel S NewsonMedical Affairs, Eli Lilly and Company, Sydney, New South Wales, Australia.
Esther ArtimeVEO, Eli Lilly and Company, Alcobendas, Community of Madrid, Spain.ORCID 0000-0003-4294-6462
Julie BowerMedical Affairs, Eli Lilly and Company, Indianapolis, IN, USA.
Erik SpaepenHaaPACS GmbH, Schriesheim, Baden-Württemberg, Germany.
Birong LiaoMedical Affairs, Eli Lilly and Company, Indianapolis, IN, USA.ORCID 0000-0002-6336-8940
Indranil BhattacharyaMedical Affairs, Eli Lilly and Company, Gurgaon, Haryana, India.
Tadej BattelinoUniversity Medical Center Ljubljana, and Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This analysis aimed to document suboptimal insulin dosing (missed or skipped and mistimed basal and/or bolus) in people with diabetes (PwD), including type 1 diabetes (T1D) and type 2 diabetes (T2D). Additionally, barriers and solutions for optimal insulin dosing were explored. Patients and Methods: This multinational, cross-sectional, online survey was conducted in the United States, the United Kingdom, and Germany. Eligible PwD with T1D or T2D used an analog insulin pen. Data were analyzed using descriptive statistics. Results: A total of 1150 PwD (T1D: 300; T2D: 850) were included. Overall, a proportion of PwD reported missing 1 or more basal (48.2%) or bolus dose (59.6%) in the past 30 days. Among those who reported missing doses, the average number [standard deviation] was 3.6 [3.6] basal doses and 4.6 [7.4] bolus doses. PwD reported forgetting, being too busy/distracted, and finding it too complicated or burdensome as key reasons for missed doses. A proportion of PwD reported mistiming 1 or more basal (45.7%) dose or bolus (53.6%) dose in the past 30 days. Among those who reported mistiming doses, the average was 3.9 [4.0] basal and 5.1 [8.1] bolus doses. Key reasons reported for mistiming doses included being too busy or distracted, being out of routine, or having an unexpected or earlier/later-than-expected meal. Conclusion: Suboptimal insulin use is prevalent among PwD, with nearly half of participants reporting missed or mistimed doses in the past 30 days. Results indicate the need for support to help PwD self-manage the complexity of insulin treatment and to improve outcomes due to suboptimal insulin dosing. Such support might include devices that record measurements and dosing and provide feedback.

Indexed as

basalbolusdiabetesmissed dosesmistimed dosessuboptimal dosing

Identifiers

PMID40476160
PMCPMC12139093

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.