ArticleCureus2025
Histological and Morphological Evaluation of Exfoliated Silver Diamine Fluoride-Treated Carious Primary Teeth.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silver diamine fluoride (SDF) is a minimally invasive treatment modality that has gained attention in recent years owing to its remineralizing capability. However, there is limited research on its effect at a microscopic level. This case series presents three cases of exfoliated primary teeth where histologic and morphological analysis was performed after a single application of SDF on carious dentin. This paper provides valuable insights into the long-term and sustained effectiveness of SDF, making it a cost-effective treatment for young, uncooperative children including those with special health care needs. In addition, it also highlights that periodic re-application of SDF can enhance the overall caries-arresting potential. However, despite the clinical success, the inclusion of silver particles deep within the dentinal tubules results in pronounced discoloration, which is a significant drawback of SDF. Future research has to be directed toward innovative techniques to overcome discoloration while maintaining its efficacy.
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Registered trials
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