ArticleCureus2025
Evaluation of Nutritional Status During Induction Chemotherapy in Patients With Acute Leukemia.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition is often prevalent in most of the children living in resource-limited countries. This study aimed to evaluate the occurrence of malnutrition and micronutrient deficiency in patients with acute leukemia undergoing induction chemotherapy and to report the various outcomes regarding complications and remission rates. MATERIALS AND
methodsThis prospective observational study was conducted at the hematology wards of All India Institute of Medical Sciences (AIIMS), New Delhi from February 2018 to August 2019. The study involved children and adolescents aged two to 20 years, of any gender, diagnosed with acute leukemia, and undergoing induction chemotherapy. Baseline characteristics were recorded along with nutritional parameters like micronutrients at admission, two weeks, and four weeks (at the end of induction).
resultsA total of 64 patients were enrolled, and the majority of them were males (67.18%). Based on body mass index (BMI), patients were categorized into underweight (45.31%), healthy weight (51.56%), and overweight (3.13%) groups. B-cell acute lymphoblastic leukemia (B-ALL) was the most common diagnosis. There was a noticeable trend of worsening undernutrition in both underweight and healthy weight groups. The mean BMI decreased significantly from 16.71 kg/m
conclusionThe study highlights the critical importance of assessing and addressing the nutritional status of acute leukemia patients upon admission, as undernourished individuals exhibited higher morbidity and required more chemotherapy dose adjustments.
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