Evidence map›Paper›PMID 40476076›Full record

ArticleSynthetic and systems biotechnology2025

Shanshan Zhao, Zefei Wang, Liyan Tian, Kejing Li, Shiwei Sun, Gen Chen, Daoqiong Zheng

Abstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shanshan ZhaoDonghai Laboratory, Zhoushan, Zhejiang 316021, China.
Zefei WangInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan, 316021, China.
Liyan TianInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan, 316021, China.
Kejing LiInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan, 316021, China.
Shiwei SunInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan, 316021, China.
Gen ChenInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan, 316021, China.
Daoqiong ZhengInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan, 316021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chaetoglobosin A (cheA) is a complex indole alkaloid exhibiting preferential cytotoxicity against plant pathogens, parasites, and tumor cells. However, the limited production and high synthesis costs of cheA impede its widespread application. Tryptophan serves as a precursor for cheA biosynthesis, and strategic modification of the expression of key genes represents a novel approach to enhance the target yield. Herein,

Indexed as

Anthranilic acid synthaseChaetoglobosin AChaetomium globosum W7MetabolomeTryptophan

Identifiers

PMID40476076
PMCPMC12139454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.