Evidence map›Paper›PMID 40476054›Full record

ArticleFrontiers in surgery2025

One year mortality after pediatric hydrocephalus treatment: a comparative analysis of endoscopic third ventriculostomy and ventriculoperitoneal shunt.

Ahmad Alali, Wesam Alkabouni, Viktoria Aretz, Timo Volpert, Yollam Makanjira, Martin Kampeni, Thomas Kapapa, Patrick Kamalo

Abstract read
In one paragraph

Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmad AlaliDepartment of Neurosurgery, Ulm University Hospital, Ulm, Germany.
Wesam AlkabouniDepartment of Neurosurgery, Ulm University Hospital, Ulm, Germany.
Viktoria AretzDepartment of Neurosurgery, Ulm University Hospital, Ulm, Germany.
Timo VolpertDepartment of Neurosurgery, Ulm University Hospital, Ulm, Germany.
Yollam MakanjiraBlantyre Institute of Neurosurgical Sciences, Blantyre, Malawi.
Martin KampeniBlantyre Institute of Neurosurgical Sciences, Blantyre, Malawi.
Thomas KapapaDepartment of Neurosurgery, Ulm University Hospital, Ulm, Germany.
Patrick KamaloBlantyre Institute of Neurosurgical Sciences, Blantyre, Malawi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Management options for hydrocephalus have increased to include endoscopic third ventriculostomy with or without choroid plexus cauterization (ETV ± CPC) in addition to traditional ventrikuloperitoneal shunting (VPS). This study evaluates the mortality and complications of these procedures in pediatric hydrocephalus, offering insights for clinical decision-making in a low-income country context. Methods: We retrospectively reviewed the operating theatre registry for infants under 1 year of age who underwent initial hydrocephalus surgery in a tertial sub-Saharan hospital in 2021. Follow-up was conducted for up to 1 year after surgery, confirming the patient's vital status (alive or dead) through hospital visits, contact information, and medical records. Descriptive analyses evaluated outcomes (mortality and complications), and survival was assessed using the Kaplan-Meier method with log-rank testing. Results: A total of 127 patients were included, with 71 males (55.91%). Complete 1-year follow-up data was available for 94 (74%) patients. Of these, 35 (37.23%) underwent ETV ± CPC and 59 (62.77%) underwent VPS. The one-year survival rate was 80% (95% CI: 66.75%-93.25%) for those treated with ETV ± CPC as a definitive treatment and 78% (95% CI: 67.43%-88.57%) for those who received VPS. There was no statistically significant difference in survival rates between the two groups (Log-Rank test Conclusion: ETV ± CPC and VPS demonstrated similar survival rates, with no significant statistical difference between the two methods. However, ETV ± CPC failure often required conversion to VPS, highlighting the importance of managing shunt-related complications like sepsis and dysfunction. Careful post-operative monitoring is essential for both procedures.

Indexed as

ETV = endoscopic third ventriculostomyhydrocefalusMalawineurosurgeryventriculo peritoneal shunt

Identifiers

PMID40476054
PMCPMC12137355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.