Evidence map›Paper›PMID 40476040›Full record

ArticleOncology letters2025

Factors influencing pathological complete response to neoadjuvant chemotherapy in resectable breast cancer: A retrospective study.

Jian Kang, Huifen Xiong, Xiaoliu Jiang, Zhaohui Huang, Yonghong Guo, Yali Cao, Jingxian Ding

Abstract read
In one paragraph

Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jian KangDepartment of Radiation Oncology, The Breast Cancer Institute, Nanchang People's Hospital, Nanchang, Jiangxi 330025, P.R. China.
Huifen XiongDepartment of Radiation Oncology, The Breast Cancer Institute, Nanchang People's Hospital, Nanchang, Jiangxi 330025, P.R. China.
Xiaoliu JiangDepartment of Radiation Oncology, The Breast Cancer Institute, Nanchang People's Hospital, Nanchang, Jiangxi 330025, P.R. China.
Zhaohui HuangDepartment of Radiation Oncology, The Breast Cancer Institute, Nanchang People's Hospital, Nanchang, Jiangxi 330025, P.R. China.
Yonghong GuoDepartment of Radiation Oncology, Affiliated Rehabilitation Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Yali CaoDepartment of Breast Surgery, The Breast Cancer Institute, Nanchang People's Hospital, Nanchang, Jiangxi 330025, P.R. China.
Jingxian DingDepartment of Radiation Oncology, The Breast Cancer Institute, Nanchang People's Hospital, Nanchang, Jiangxi 330025, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoadjuvant chemotherapy (NAC) is widely used to treat breast cancer and a pathological complete response (pCR) following NAC is associated with an optimal prognosis; however, pCR rates vary significantly. In the present study, the effects of clinicopathological factors and the administration of different taxanes on pCR rates in patients with resectable breast cancer were assessed. A total of 552 patients with breast cancer who received NAC between May 2019 and June 2024 were included in the present study. The clinicopathological traits of the patients were retrieved from medical records and their association with the pCR rate was evaluated using univariate and multivariate regression analyses. The efficacy of nanoparticle albumin-bound (Nab)-paclitaxel, docetaxel and paclitaxel liposomes in different subtypes of breast cancer were further evaluated. A total of 189 of 552 (34.2%) patients achieved pCR following NAC. The pCR rate varied significantly among different molecular subtypes as follows: 58.9% (96/163), 40.7% (37/91), 35.6% (37/104) and 9.8% (19/298) among patients with hormone receptor (HR) negative (-) human epidermal growth factor receptor 2 (HER2) positive (+), HR

Indexed as

breast cancerneoadjuvant chemotherapypathological complete responsetaxane

Identifiers

PMID40476040
PMCPMC12138496

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.