Evidence map›Paper›PMID 40476030›Full record

ArticleOpen forum infectious diseases2025

Infectious Complications of Substance Use: A Retrospective Cohort Study of Hospitalized Veterans.

Leah Harvey, Hassen Abdulkerim, Judith Strymish, Samantha K Ryan, Jacqueline Boudreau, Allen Gifford, Justeen Hyde, Westyn Branch-Elliman

Registry-linked trialAbstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05020418 (Promoting De-Implementation of Inappropriate Antimicrobial Use in Cardiac Device Procedures By Expanding Audit and Feedback), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05020418 nacompletednot on this map

Promoting De-Implementation of Inappropriate Antimicrobial Use in Cardiac Device Procedures By Expanding Audit and Feedback

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2023 to 2025Enrolled5,469ConditionsAntibiotics Causing Adverse Effects in Therapeutic UseArmsChart Review
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leah HarveyDivision of Infectious Diseases, Department of Medicine, Alpert School of Medicine at Brown University, Providence, Rhode Island, USA.ORCID https://orcid.org/0000-0003-3120-3065
Hassen AbdulkerimCenter for Health Optimization and Implementation Research, VA Boston Healthcare System, US Department of Veterans Affairs . Boston, Massachusetts, USA.
Judith StrymishDepartment of Medicine, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-3711-0639
Samantha K RyanCenter for Health Optimization and Implementation Research, VA Boston Healthcare System, US Department of Veterans Affairs. Boston, Massachusetts, USA.
Jacqueline BoudreauCenter for Health Optimization and Implementation Research, VA Bedford Healthcare System, US Department of Veterans Affairs, Bedford, Massachusetts, USA.
Allen GiffordCenter for Health Optimization and Implementation Research, VA Boston Healthcare System, US Department of Veterans Affairs. Boston, Massachusetts, USA.
Justeen HydeCenter for Health Optimization and Implementation Research, VA Bedford Healthcare System, US Department of Veterans Affairs, Bedford, Massachusetts, USA.
Westyn Branch-EllimanCenter for Health Optimization and Implementation Research, VA Boston Healthcare System, US Department of Veterans Affairs. Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-9658-5124

Funding

BU Clinical HIV/AIDS Research Training Program (BU-CHART)T32AI052074 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Benjamin P. Linas · 2003 to 2026
$6.7M
Advancing Clinical Research Training within Addiction Residency ProgramsR25DA033211 · NIDA · BOSTON MEDICAL CENTER · PI Patrick O'Connor, JEFFREY H. SAMET · 2012 to 2026
$4.2M
The Lifespan/Brown Criminal Justice Research Program on Substance Use and HIVR25DA037190 · NIDA · MIRIAM HOSPITAL · PI CURT G BECKWITH · 2014 to 2026
$3.5M
K12 Cardiopulmonary Implementation Science Scholars ProgramK12HL138049 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEMON, STEPHENIE C., LINDENAUER, PETER KYLE · 2017 to 2021
$2.7M
NHLBI NIH HHS K12 HL138049NIAID NIH HHS T32 AI052074NIDA NIH HHS R25 DA033211NIDA NIH HHS R25 DA037190
6 · The paper itself

Abstract

Invasive bacterial infections (IBI) associated with drug use are increasing, but the full disease burden remains unknown. We characterized national trends in the prevalence of IBI among veterans with evidence of substance use using a large, national cohort. High rates of IBI highlight a need for more comprehensive infection reduction strategies, including emphasis on gram-negative infections.

Indexed as

bacteremiablood stream infectionssubstance use

Identifiers

PMID40476030
PMCPMC12138505

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.