Evidence map›Paper›PMID 40475730›Full record

ReviewReviews in cardiovascular medicine2025

The Emerging Role of Computed Tomography Coronary Angiography in the Left Main Stem Percutaneous Coronary Intervention.

Asad Shabbir, Abdelrahman Attia, Nikkole Marie Weber, Mustafa Alhassan, Monika Radike, Conor M Lane, Apurva Bhavana Challa, Malgorzata Wamil

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asad ShabbirJohn Radcliffe Hospital, Oxford University Hospitals, OX3 9DU Oxford, UK.
Abdelrahman AttiaCardiology Department, Great Western Hospital NHS Trust, SN3 6BB Swindon, UK.
Nikkole Marie WeberRadiology Department, Mayo Clinic Rochester, Rochester, MN 55903, USA.
Mustafa AlhassanCardiology Department, Great Western Hospital NHS Trust, SN3 6BB Swindon, UK.
Monika RadikeRadiology Department, Mayo Clinic Rochester, Rochester, MN 55903, USA.
Conor M LaneRadiology Department, Mayo Clinic Rochester, Rochester, MN 55903, USA.
Apurva Bhavana ChallaRadiology Department, Mayo Clinic Rochester, Rochester, MN 55903, USA.
Malgorzata WamilCardiology Department, Great Western Hospital NHS Trust, SN3 6BB Swindon, UK.ORCID https://orcid.org/0000-0002-5361-2532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advancements in computed tomography have significantly transformed the clinical application of this technique in diagnosing and managing coronary artery disease (CAD). Computed tomography coronary angiography (CTCA) has emerged as a leading non-invasive imaging modality, often serving as the first-line investigation to exclude obstructive CAD in patients with chronic coronary syndrome. Beyond its utility in diagnosing CAD, CTCA has become instrumental in procedural planning for percutaneous coronary intervention (PCI), particularly in complex cases such as left main stem (LMS) interventions, where peri-procedural risks are elevated. This review highlights the evolving role of CTCA in LMS PCI, underscoring its clinical utility in improving procedural precision and, subsequently, patient outcomes. Recent technological advancements, including detailed multiplanar and three-dimensional (3D) reconstructions, CT-derived fractional flow reserve (CTFFR), and the integration of artificial intelligence (AI) algorithms, have expanded the capabilities of CTCA. These innovations allow for comprehensive anatomical and functional assessments, enabling precise plaque morphology, lesion complexity, and bifurcation anatomy evaluations alongside PCI simulations. By offering detailed insights into coronary vasculature and lesion characteristics, CTCA provides critical information for optimising LMS PCI strategies. This review explores the current applications and future potential of CTCA in guiding LMS PCI, highlighting its role in improving procedural planning, risk assessment, and overall management of this challenging patient population.

Indexed as

computed tomography coronary angiographycomputed tomography derived fractional flow reservecoronary artery diseaseleft main stem percutaneous coronary interventionplaque characterisation

Identifiers

PMID40475730
PMCPMC12135667

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.