Evidence map›Paper›PMID 40475688›Full record

ArticleRadiology case reports2025

Thalamic pleomorphic xanthoastrocytoma central nervous system World Health Organization grade 3.

Hirotaka Takita, Taro Shimono, Kosuke Nakajo, Tsutomu Ichinose, Sayaka Tanaka, Junko Hirato, Hayato Ikota, Maciej Pas, Haruna Sakamoto, Shodai Hiramatsu and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hirotaka TakitaDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Taro ShimonoDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Kosuke NakajoDepartment of Neurosurgery, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Tsutomu IchinoseDepartment of Neurosurgery, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Sayaka TanakaDepartment of Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Junko HiratoDepartment of Pathology, Public Tomioka General Hospital, 2073-1, Tomioka, Tomioka, Gunma, 370-2316, Japan.
Hayato IkotaClinical Department of Pathology, Gunma University Hospital, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Maciej PasDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Haruna SakamotoDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Shodai HiramatsuDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Yukio MikiDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic tumor. According to the 2021 World Health Organization (WHO) classification of central nervous system (CNS) tumors, PXAs with 5 or more mitoses per 10 high-power fields are classified as CNS WHO grade 3. Imaging findings of PXA CNS WHO grade 3 have rarely been reported, and thalamic cases are particularly uncommon. We present a case of thalamic PXA CNS WHO grade 3. A 71-year-old male presented with progressive right hemiparesis over three months. Magnetic resonance imaging (MRI) revealed a mass lesion in the left thalamus. Due to rapid tumor growth causing obstructive hydrocephalus, he underwent urgent craniotomy for tumor resection. Histopathology confirmed a PXA CNS WHO grade 3. Postoperatively, the patient received 54 Gy of radiation therapy in 27 fractions. His right hemiparesis persisted. He was subsequently transferred to a rehabilitation hospital.

Indexed as

Pleomorphic xanthoastrocytomaThalamusThe 2021 World Health Organization classification of central nervous system tumors

Identifiers

PMID40475688
PMCPMC12138516

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.