Evidence map›Paper›PMID 40475467›Full record

ArticlebioRxiv : the preprint server for biology2025

Isoform-Specific Gene Regulation by Progesterone Receptors Drives Divergent Phenotypes in Breast Cancer Cells.

Noelle E Gillis, Thu H Truong, Caroline H Diep, Angela Spartz, Julie H Ostrander, Carol A Lange

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Noelle E GillisUniversity of Minnesota, Masonic Cancer Center, Minneapolis, MN 55455, USA.
Thu H TruongUniversity of Minnesota, Masonic Cancer Center, Minneapolis, MN 55455, USA.
Caroline H DiepUniversity of Minnesota, Masonic Cancer Center, Minneapolis, MN 55455, USA.
Angela SpartzUniversity of Minnesota, Masonic Cancer Center, Minneapolis, MN 55455, USA.
Julie H OstranderUniversity of Minnesota, Masonic Cancer Center, Minneapolis, MN 55455, USA.
Carol A LangeUniversity of Minnesota, Masonic Cancer Center, Minneapolis, MN 55455, USA.ORCID 0000-0002-0005-4194

Funding

Progesterone Receptor (PR) Signaling Cross Talk Drives ER+ Breast CancerR01CA229697 · NCI · UNIVERSITY OF MINNESOTA · PI Carol A Lange, Douglas Yee · 2020 to 2026
$3.6M
SRC-3/PELP1 complexes drive stem-like phenotypes in luminal breast cancerR01CA236948 · NCI · UNIVERSITY OF MINNESOTA · PI LANGE, CAROL A, OSTRANDER, JULIE H · 2020 to 2024
$2.4M
Targeting Oncogenic PELP1/SRC-3 Signaling Complexes in ER+ Breast CancerK22CA248615 · NCI · UNIVERSITY OF MINNESOTA · PI TRUONG, THU HA · 2023 to 2025
$605k
Nuclear Receptor Regulation of Epigenetics in Endocrine-Related CancersK00CA245796 · NCI · UNIVERSITY OF MINNESOTA · PI GILLIS, NOELLE ELIZABETH · 2021 to 2024
$366k
NCI NIH HHS K00 CA245796NCI NIH HHS K22 CA248615NCI NIH HHS R01 CA229697NCI NIH HHS R01 CA236948
6 · The paper itself

Abstract

Exposure to progesterone is a recognized risk factor for breast cancer, and

Identifiers

PMID40475467
PMCPMC12139888

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.