Evidence map›Paper›PMID 40475454›Full record

ArticlebioRxiv : the preprint server for biology2025

Molecular Control of Non-Muscle Myosin II-A Aggregation and Intracellular Dynamics by motor- or tail-specific

Clara Llorente-González, Kamila Mustafina, Vanessa C Talayero, Gloria Asensio-Juárez, Marina Garrido-Casado, James R Sellers, Krishna Chinthalapudi, Paul W Wiseman, Sarah M Heissler, Miguel Vicente-Manzanares

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Clara Llorente-GonzálezMolecular Mechanisms Program, Centro de Investigación del Cáncer/ Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-1338-6585
Kamila MustafinaDepartment of Chemistry, McGill University, Montréal, Québec, Canada.ORCID 0000-0001-5892-7579
Vanessa C TalayeroMolecular Mechanisms Program, Centro de Investigación del Cáncer/ Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca, 37007 Salamanca, Spain.
Gloria Asensio-JuárezMolecular Mechanisms Program, Centro de Investigación del Cáncer/ Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-3081-668X
Marina Garrido-CasadoMolecular Mechanisms Program, Centro de Investigación del Cáncer/ Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca, 37007 Salamanca, Spain.
James R SellersCell and Developmental Biology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Krishna ChinthalapudiDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID 0000-0003-3669-561X
Paul W WisemanDepartment of Chemistry, McGill University, Montréal, Québec, Canada.
Sarah M HeisslerDepartment of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID 0000-0002-6972-7940
Miguel Vicente-ManzanaresMolecular Mechanisms Program, Centro de Investigación del Cáncer/ Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-5943-3220

Funding

Structure and function of nonmuscle myosinsR01GM143539 · NIGMS · OHIO STATE UNIVERSITY · PI CHINTHALAPUDI, KRISHNA · 2021 to 2025
$2.1M
Molecular Mechanisms of Myosin-3R01GM143414 · NIGMS · OHIO STATE UNIVERSITY · PI HEISSLER, SARAH · 2021 to 2025
$1.7M
ROLE OF PHOSPHORYLATION AS A REGULATORY MECHANISM IN MUSCLE CONTRACTIONZ01HL001786 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SELLERS, JAMES R. · 1985 to 2008
$601k
Intramural NIH HHS Z01 HL001786NIGMS NIH HHS R01 GM143414NIGMS NIH HHS R01 GM143539
6 · The paper itself

Abstract

Mutations in the

Identifiers

PMID40475454
PMCPMC12139846

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.