ArticlebioRxiv : the preprint server for biology2025
Circadian Control of Sleep by Melatonin via MT
Kiranmayi Vedantham, Adeel Ahmad, Longgang Niu, Yuan Shui, Fouad Lemtiri-Chlieh, Deborah Kaback, Xin-Ming Ma, Xiangyou Hu, Siu-Pok Yee, Zhao-Wen Wang
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Kiranmayi VedanthamDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.ORCID 0009-0003-0828-6445 Adeel AhmadDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.
Longgang NiuDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.ORCID 0000-0001-7209-7436 Yuan ShuiDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.
Fouad Lemtiri-ChliehDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.
Deborah KabackCenter of Mouse Genome Modification, University of Connecticut School of Medicine, Farmington, CT, USA.
Xin-Ming MaDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.
Xiangyou HuDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.
Siu-Pok YeeCenter of Mouse Genome Modification, University of Connecticut School of Medicine, Farmington, CT, USA.ORCID 0000-0002-2427-401X Zhao-Wen WangDepartment of Neuroscience, University of Connecticut School of Medicine, Farmington, CT, USA.
Funding
Synaptic function of BK channel-interacting proteinsR01MH085927 · NIMH · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ZHAO-WEN WANG · 2010 to 2026
$6.7MThe function of gap junctions and chemical synapses in a simple neural circuitR01NS109388 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WANG, ZHAO-WEN · 2018 to 2022
$2.0MNIMH NIH HHS R01 MH085927NINDS NIH HHS R01 NS109388
6 · The paper itselfAbstract
Melatonin promotes sleep through mechanisms that have remained elusive. Here, we identify a molecular pathway by which melatonin promotes sleep by activating BK channels (Slo1) via MT
Identifiers
PMID40475449
PMCPMC12139804
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