Evidence map›Paper›PMID 40475334›Full record

ArticleCase reports in dermatological medicine2025

A Case of Erythrodermic Psoriasis Successfully Treated With Ixekizumab Combined With Low-Dose Methotrexate to Ensure Sustained Clearance: A Case Report.

Jennifer Lavina Ngo, Lily Lyralin Tumalad, Patricia Anne Tinio, Rogelio Balagat

Abstract readCase Reports
In one paragraph

Article in Case reports in dermatological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer Lavina NgoDepartment of Dermatology, Rizal Medical Center, Pasig, Philippines.ORCID https://orcid.org/0000-0002-1831-3385
Lily Lyralin TumaladDepartment of Dermatology, Rizal Medical Center, Pasig, Philippines.ORCID https://orcid.org/0000-0003-4271-7803
Patricia Anne TinioDepartment of Dermatology, Rizal Medical Center, Pasig, Philippines.
Rogelio BalagatDepartment of Dermatology, Rizal Medical Center, Pasig, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erythrodermic psoriasis (EP) is a severe type of psoriasis that requires immediate and effective treatment to prevent serious complications. Although recommended as first-line treatment for EP, conventional systemic disease-modifying antirheumatic drugs (csDMARDs) such as methotrexate and/or cyclosporine can sometimes be ineffective or undesirable, hence the use of biologics. However, in cases of refractory disease, biologics may be combined with methotrexate to boost efficacy and optimize outcomes without compromising safety and tolerability.

Indexed as

biologicscombination treatmenterythrodermic psoriasisixekizumabmethotrexate

Identifiers

PMID40475334
PMCPMC12140818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.