Evidence map›Paper›PMID 40475319›Full record

Reviewnpj biological physics and mechanics2025

Cellular mechanisms of traumatic brain injury.

Gia Kang, Eng Kuan Moo, Rohan Banton, Oren E Petel, Andrew R Harris

Abstract readReview
In one paragraph

Review in npj biological physics and mechanics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Pathway-level proteomics identifies subcellular trafficking dysregulation as a molecular signature in severe traumatic brain injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gia KangDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, ON, K1S 5B6 Canada.
Eng Kuan MooDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, ON, K1S 5B6 Canada.
Rohan BantonU.S. Army Research Laboratory, Aberdeen Proving Ground, Aberdeen, MD 21005-5066 USA.
Oren E PetelDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, ON, K1S 5B6 Canada.
Andrew R HarrisDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, ON, K1S 5B6 Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild traumatic brain injury (mTBI) is an acute injury with immediate and medium-term symptom presentation. However, our mechanistic understanding of mTBI and how mechanical loading of soft cellular tissues leads to injury is limited. The aim of this review is to introduce this interdisciplinary field to non-experts and provide an overview of our current understanding of how mechanical trauma contributes to cellular injury. Here, we compare the significance of various measures of mechanical loading including strain magnitude, strain rate, loading mode, and frequency, and their relative significance for cell and tissue injury in

Indexed as

Biological techniquesBiophysicsDiseases

Identifiers

PMID40475319
PMCPMC12133593

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.