ReviewPeerJ2025
Potential role of photobiomodulation as a prevention and treatment strategy for radiation induced fibrosis: a review of effectiveness and mechanisms.
Review in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Radiation induced fibrosis (RIF) is a chronic progressive disabling side effect of radiation therapy in cancer survivors with limited therapeutic options. Photobiomodulation therapy (PBMT) is being propagated as a non-invasive therapeutic option but has limited evidence. This scoping review aims to summarize the effects and mechanisms of PBMT in the prevention and treatment of RIF. Methods: A systematic search was conducted across five databases (PubMed, Scopus, EBSCO, ProQuest, LILACS), and three other platforms (Google Scholar, ResearchGate, Academia.edu). Retrieved studies underwent independent title, abstract, full text screening and data extraction. Quality analysis was performed for human studies to assess methodological rigor. Results: The review identified three studies that specifically focused on RIF. Since induction of RIF is not common for Conclusion: PBMT demonstrates potential as a non-invasive, safe therapeutic option for RIF, supported by extensive preclinical evidence. However, high-quality clinical trials are necessary to validate its clinical efficacy. Implication: PBMT offers a promising intervention for managing RIF, with potential to enhance body image, self-confidence, functional abilities, and overall quality of life for cancer survivors. This review underscores the need for further research to translate these findings into clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.